The Pierre Auger Observatory is the largest facility in the world to study ultra-high-energy cosmic rays. It has a hybrid detection technique that combines the observation of the longitudinal development of extensive air showers and the measurement of their particles at the ground. This capability has opened the possibility to probe hadronic interactions taking place at energies well beyond those accessible by human-made accelerators. In this report, we present a selection of the latest results on hadronic interactions with measurements from the Pierre Auger Observatory. These data span over three decades in energy, showing the tension between data from the muon component of air showers and predictions based on the most updated hadronic interaction models.