The study by Schultz et al 1 adds to mounting evidence suggesting the effectiveness of robust surveillance and response programs, such as those implemented for collegiate athletes, in combating the COVID-19 pandemic. 1 The authors analyzed SARS-CoV-2 testing data for students from select colleges and universities in the US during the 2020 to 2021 academic year, comparing athletes with nonathletes. Despite the high-risk nature of activities in which athletes are engaged, almost all schools reported lower positivity among athletes compared with their nonathlete counterparts. Of 4 million SARS-CoV-2 tests at 12 US institutions, an overall 50% risk reduction was observed in athletic program testing, suggesting that collegiate athletics programs were associated with a protective outcome during the COVID-19 pandemic. Concern over the health of college athletes is certainly not new; it is a routine subject of health-preservation initiatives by athletic conferences, university policies, and individual athletic programs. However, in the time of COVID-19, the National Collegiate Athletic Association (NCAA) led with early and aggressive recommendations for contact tracing, isolation, and quarantine in an effort to monitor, mitigate, and manage SARS-CoV-2 infections and exposures. 2 There is an ongoing and growing interest in the association of such efforts with SARS-CoV-2 infection and transmission.Athletics activities, from training to competition, present constant challenges to the control of infectious diseases. Sports-associated events and activities can facilitate airborne, respiratory, person-to-person, and environmental transmission of viruses, bacteria, and other agents, including those with outbreak potential. Physical contact, close proximity, increased respiration, shared equipment and facilities, and travel-related experiences may aid transmission among players, athletic