Introduction: Fibro-osseous lesion (FOL) is a broad term for a diverse group of jaw and craniofacial disorders that are often painless but grow progressively if uncontrolled. They are characterized by the replacement of normal bone by fibrous connective tissue matrix displaying varying degrees of mineralization in the form of woven bone or cementum-like structures. Patients and Methods: Retrospective survey of the records of all patients seen between 2000 and 2013 at the department of Oral and Maxillofacial Surgery clinic, Ahmadu Bello University Teaching Hospital Zaria, Nigeria was undertaken. Results: A total of 104 patients were seen over the period of study. Of these, males comprised 40 and female, 64 giving a male to female ratio of 1:1.6. The age ranged from 4-66 years, mean 25.8 (13.21) years. There was no gender difference in terms of age (t=1.78; P=0.078). Fibrous dysplasia was the most predominant lesion and accounted for 60 (57.7%) of the cases and this was followed by ossifying fibroma (n=39; 37.5%). Conclusion: Due to late presentation, the size of the lesion, the outcome is usually not good esthetically especially for maxillary lesions.