Relevance: Cardioembolism is one of the major causes of ischemic strokes and accounts for 15-30% of all cerebral infarctions. Atrial fibrillation (AF) accounts for up to 60% of cardioembolic strokes. Assessing thromboembolic risk is important for patients with AF; however, these concerns do not apply equally to men and women. The study aimed to determine gender differences in echocardiographic and computed tomography characteristics of patients with atrial fibrillation. Methods: The included 202 patients underwent both transthoracic echocardiography and computed tomography. We excluded patients with allergies to iodide, increased creatinine levels, hyperthyroidism, pregnancy, and age <18 years. Results: An increase in BMI by 1 kg/m2 in female patients increased the risk of left-atrium appendage (LAA) thrombus by 10% (OR=1,1, p=0.019). The yearly increase in the age of women lowers the risk of LAA thrombosis by 6% (OR=0,94, р=0,01). Each increase of EDD in women to 1 cm raises the risk of LAA thrombosis by 151% (OR=2,51, p=0.031). Each increase of ESV and EDV in women to 1 ml raises the risk of LAA thrombosis by 4% and 3%, respectively (p<0.05). Each increase of LVESVI and LVEDVI in female patients to 1 ml/m2 raises the risk of LAA thrombosis by 6% and 5%, respectively (p<0.05). Older age, higher CHA2 -DS2 -VASc, HAS-BLED scores, and enlarger LA in male patients were significantly associated with LAA thrombosis. The yearly increase in the age of men increases the risk of LAA thrombosis by 5% (OR=1.05, p=0.012). Men with coronary atherosclerosis at risk of thrombosis by 224% (OR=3,24, p=0.002). Conclusion: Understanding gender differences may help clinicians provide better care to individuals with AF

Relevance: Cardioembolism is one of the major causes of ischemic strokes and accounts for 15-30% of all cerebral infarctions. Atrial fibrillation (AF) accounts for up to 60% of cardioembolic strokes. Assessing thromboembolic risk is important for patients with AF; however, these concerns do not apply equally to men and women. The study aimed to determine gender differences in echocardiographic and computed tomography characteristics of patients with atrial fibrillation. Methods: The included 202 patients underwent both transthoracic echocardiography and computed tomography. We excluded patients with allergies to iodide, increased creatinine levels, hyperthyroidism, pregnancy, and age <18 years. Results: An increase in BMI by 1 kg/m2 in female patients increased the risk of left-atrium appendage (LAA) thrombus by 10% (OR=1,1, p=0.019). The yearly increase in the age of women lowers the risk of LAA thrombosis by 6% (OR=0,94, р=0,01). Each increase of EDD in women to 1 cm raises the risk of LAA thrombosis by 151% (OR=2,51, p=0.031). Each increase of ESV and EDV in women to 1 ml raises the risk of LAA thrombosis by 4% and 3%, respectively (p<0.05). Each increase of LVESVI and LVEDVI in female patients to 1 ml/m2 raises the risk of LAA thrombosis by 6% and 5%, respectively (p<0.05). Older age, higher CHA2 -DS2 -VASc, HAS-BLED scores, and enlarger LA in male patients were significantly associated with LAA thrombosis. The yearly increase in the age of men increases the risk of LAA thrombosis by 5% (OR=1.05, p=0.012). Men with coronary atherosclerosis at risk of thrombosis by 224% (OR=3,24, p=0.002). Conclusion: improved clinician understanding of gender differences may help clinicians better care for individuals with AF

<b>Objective: </b>Atrial fibrillation is strongly associated with stroke and accounts for 60% of cardioembolic stroke. Assessing thromboembolic risk is important for patients with atrial fibrillation. Approximately 90% of all thrombus are localized in the left atrium appendage (LAA). This study aimed to determine the efficacy of cardiac computed tomography (CT) for LAA thrombus detection.<br /> <b>Material and methods:</b> This retrospective study included 292 patients. LAA thrombus was confirmed or excluded by cardiac CT with the reference to transesophageal echocardiography (TEE). We excluded patients with allergic reactions to iodide, increased creatinine levels, thyroid disease (hyperthyroidism), pregnancy, and age &lt;18 years.<br /> <b>Results:</b> According to the cardiac CT, 103 of 292 people had LAA thrombus, while according to TEE, only 48 of patients had LAA thrombus. The sensitivity and specificity of CT were 97.7% and 77%, respectively. The sensitivity and specificity of the CT was higher in 2016–2020, when the delayed phase was added to the standard protocol, compared to 2012–2015 years. Older age, higher BMI, higher CHA₂DS₂-VASc and HAS-BLED scores, and larger LA and LVESV were significantly associated with LAA thrombus detection on cardiac CT. Higher LVESV and LVEDV indexes (LVESVI and LVEDVI) and lower LV ejection fraction measured by TEE were also predictors of LAA thrombus detection by cardiac CT.<br /> <b>Conclusion:</b> Our findings show that cardiac CT has high sensitivity and specificity for excluding or confirming LAA thrombus, and can also be exclusively used to determine the presence or absence of a thrombus.