This was a pilot, single blind, randomised, controlled study in patients requiring partial meniscectomy. The aim was to assess whether replacing the synovial fluid lost during arthroscopy with a hyaluronic acid-containing synovial fluid substitute (Viscoseal) would reduce the severity and duration of post-operative symptoms during the 4 weeks post-surgery, in comparison to the standard arthroscopy procedure alone. Fifty patients were randomly assigned to either undergo arthroscopic partial meniscectomy alone (control group: n=25) or to receive 10 ml Viscoseal into the joint at the end of the procedure (Viscoseal group: n=25). Forty patients (20 per group) completed the study. Despite the small patient population in this pilot study, some interesting results were obtained. On Day 1 after surgery, the mean values for pain at rest (VAS) increased in both groups but this increase was lower in the Viscoseal group (8.9+/-23.1 mm) than in the standard therapy group (20.0+/-25.9 mm) (Mann-Whitney statistic MW-S: P=0.0525) and remained in favour of Viscoseal for the first 3 days after surgery. Joint swelling decreased to a greater extent in the Viscoseal group with an observed superiority at Day 7 (MW-S: P=0.1187) and a proven superiority at Days 12 (MW-S: P=0.015) and 28 (MW-S: P=0.0072). Diclofenac intake was lower in the Viscoseal group from Day 3 to Day 28 with a proven superiority (LB-CI > 0.5) in favour of Viscoseal on Days 3 (MW-S: P = 0.0093), 4 (MW-S: P= 0.0075), and 7 (MW-S: P = 0.0195) indicating that the product had an NSAID-sparing effect. Viscoseal was safe and well-tolerated and no adverse reactions occurred during the study. These findings indicate that Viscoseal may be useful as a synovial fluid substitute after arthroscopy.
Presentation of a case of algodystrophy (i.e., Sudeck's dystrophy) of the left knee, affecting the femur, tibia and patella. It was brought on by a simple movement made while playing tennis and it recurred subsequently accompanied by algodystrophy of the corresponding foot. Histological study of the biopsy material showed the classical image of cortical and cancellous bone atrophy with non-specific remodelling which explained the increased uptake on the scintigraph as well as the repairing of the bone tissue observed on the X-rays. Reasons are given for the choice of the term algodystrophy to describe the condition.
Sciatic block with Mepivacaine (3-4 mg/kg) revealed successful in 91.9% of 340 rheumatoid patients with Keller/Clayton operation. In unsufficient blocks (8.1%) supplementary anesthesia by femoral nerve block, reblocking the sciatic nerve or local anesthetics secondarily gave good operating conditions. In three cases it was necessary to use additional spinal anesthesia. The concomitant sympathetic block gives an immediate cessation of sweating and a long lasting evaluation of skin temperature.
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