Aim:To analyze the difference of the number of neurons in the cerebrum of Rattus norvegicus offsprings exposed to Mozart, Jazz, Blues, and Rock compilations during pregnancy. Method:Experimental study with single-blind randomized post-test only control group design using Rattus norvegicusas animal subjects that were divided into four groups: Mozart, Jazz, Blues, and Rock groups. The exposures started from the 10 day of gestation for 1 hour in a dark atmosphere with an intensity of 60 dB, in a distance of 25 cm from the exposure box, during March-May 2019. After cesarean delivery at day 19, the offsprings brain were prepared and stained by Hematoxylin-Eosin, then analyzed in 5 fields in each hemisphere with 1000x magnifying microscope. The study was conducted after ethical clearance and used a comparison statistical test chosen accordingly. Result:There were significant differences of the number of neurons between Mozart (71,96 ± 14,44) with Jazz (41,06 ± 7,65), Blues(40,92 ± 6,36), and Rock group (31,31 ± 8,19) with p=0,000. Conclusion:The number of neurons in the cerebrum of Rattus norvegicus offsprings exposed to Mozart compilation during pregnancy proved to be higher than Jazz,Blues, and Rock compilations.