Abstractsearly asymptomatic or late symptomatic therapy. We describe our experience in changing from prophylactic indomethacin to late symptomatic treatment with ibuprofen. Methods We collected data on all babies admitted < 28 weeks' gestation and/or < 1000g from an electronic patient database. We compared PDA diagnosis management, demographics and clinical outcomes in two six month time periods: period 1 was when we used a prophylaxis strategy with indomethacin and period 2 when we changed to late symptomatic treatment with ibuprofen. Results Abstract 1148

Abstracts the second grade children and their parents by cluster selection method. A population of 290 children aged 6-8 years and their parents were interviewed. Results In general, the level of knowledge related to rich sources of nutrients was poor. The most of the children can't identify the role of calcium (72.6%), proteins (68.1%) and iron (84.6 %). Children prefer to eat foods they like (71.8%), such as sweets and cakes, hamburgers and etc. The most of the children (83.3%) have normal weight for age, underweight was revealed in 3.1%, overweight in 12.3% and obesity in 1.4% cases. The assessment of dietary intake show, that intake of fruits and vegetables, as well as milk and milk products is quite low, while intake of bread and pastry, and sweets are quite high. Daily consumption of sweets was significantly higher in girls (64.2%) than in boys (47.5%) (p<0.01). Only 62 % of children eat the breakfast, most children 60.4% view TV during the meal time or play computer games. The most of the children play the active games approximately 30-60 minutes, quite often children play active games only 20-30 minutes. Conclusion The dietary intake of children does not correspond to WHO recommendations. It is recommended to implement nutrition education programs for children an parents.

AbstractsAim of the work To determine the extent and severity of the aforementioned obesity-related atherosclerotic risk factors among school aged children and adolescents. Subjects and methods The sample has included 98 obese (nonsyndromic) and 36 non obese control subjects aged 6-16 years. A questionnaire was filled to evaluate the daily and weekly PA calculated in hours, anthropometry was done and blood pressure was measured, together with assessment of serum lipid profile and levels of fasting blood sugar, ALT, UA, E-selectin and hs CRP. Results 55% of obese group have shown 4 or 5 atherosclerotic RFs. One or more features of abnormal lipid profile were found in 94% of obese group with 73% showing high cholesterol level. ALT and UA were significantly higher in the obese group, similarly E-selectin that was elevated in71% of obese and hs CRP were significantly higher among obese. FBS did not show similar significant elevations. Positive correlations were found between cholesterol, E-selectin and hs CRP with BMI and waist/hip ratio. Conclusion Most of obese children and adolescents do suffer from some risk factors that can lead to an earlier and greater risk for developing atherosclerosis.