India was severely affected by the second wave of coronavirus disease (COVID‑19), leading to sudden expansive spread of Mucormycosis, presenting with sinusitis, blackish mucus secretions, discolouration of palate, facial pain, swelling and blurring of vision. Hyperglycemia, hypercoagulable state and elevated levels of serum ferritin were the major contributing factors in progression of the deadly disease. To highlight the correlation between Diabetes Mellitus, hyperferritenimia and elevated levels of D-Dimer with increased rate of incidence and poor prognosis of the disease. This study was undertaken in KLES Dr Prabhakar Kore Hospital & MRC, Belagavi, including 30 patients, between April to July 2021. Serum ferritin, HbA1C and D-Dimer were evaluated for patients on admission, along with the other routine blood investigations. The mean age was 50 years (49.99 ± 1.8), with a male predominance of 83.33% (25 Male patients). 93.33% patients had uncontrolled Diabetes Mellitus with a mean value of 10.12% (± 0.37) indicating Diabetes Mellitus to be the prime risk factor. The raised levels of serum ferritin with a mean of 662.01 ng/ml (± 129.18) and high levels of D-Dimer (Mean- 761.33 ± 151.8 ng/ml) also demonstrated their role as interlinked factors. Mucor epidemic was caused by convergence of interlinked risk factors. Awareness of red flag clinical features, prompt diagnosis, early initiation of treatment with amphotericin-B with aggressive surgical debridement are essential for successful outcome, to avoid high rate of mortality and morbidity rates in the mucormycosis patients.
<p class="abstract">Rhinocerebral mucormycosis is a saprophytic invasive fungal infection of the nose and paranasal sinuses. The angio-invasive nature of the disease and rapid spread to the surrounding vital structures makes this infection more fatal. Parotid abscess is a rare disease in both adults and children due to an ascending infection from the oral cavity via the parotid duct. Diabetes mellitus is an immuno-compromised state in which patients are more prone for several infections. Both these diseases can lead to fatal complications due to their spread and toxicity, but the one rare complication of both these diseases is Facial nerve palsy. We are presenting a case of Diabetes mellitus with Rhinocerebral mucormycosis and Parotid abscess. There have been very few documented cases of co-existing Rhinocerebral mucormycosis and Parotid abscess in a patient with facial nerve palsy as complication.</p>
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