A simple and high yielding method for the integration of a 1,2,4-triazole ring with 1,2,4-triazine-5-one (4a-j) has been developed starting from 3-arylsydnones (1a-d). The structures were proved by their spectral data and screened for antihaemostatic activity.

In the title compound, C17H13NO2, two mol­ecules crystallize in the asymmetric unit. The dihedral angle between the mean planes of the quinoline and benzene rings are 78.3 (4) and 88.2 (3)°. The carboxyl­ate group is twisted slightly from the quinoline ring by 7.1 (2) and 13.3 (4)°, respectively. In the crystal, weak C—H⋯O inter­actions are observed. Further stabilization is provided by weak π–π stacking inter­actions, with centroid–centroid distances of 3.564 (9)/3.689 (2) and 3.830 (1)/3.896 (5)Å, respectively.

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A simple and high yielding method for the integration of 1,5‐benzodiazepines integrated with 5‐methyl‐2‐oxo‐3‐phenyl‐Δ4‐1,3,4‐oxadiazolines in 75%–90% yield by microwave irradiation is devised. Microwave‐accelerated reaction was compared with thermal method. All the compounds were characterized by physical, analytical and spectral (IR, 1H NMR, MS) data. Title compounds were screened for preliminary pharmacological activities.

A simple and environmental friendly microwave irradiation method is devised for the synthesis of derivatives of 1,3,4-oxadiazoles viz., 6a-e and 7h-q in 75-90% yield. Structures of the newly synthesised compounds were confirmed by physical, analytical and spectral (ir, 1 H and 13 C nmr and ms) data and screened for antiinflammatory, anticonvulsant, antidiuretic and antihaemostatic activities. Some of the compounds have shown potent activities.