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object of this paper is to investigate the relationship between early T"" maternal deprivation and the later development of personality disorder and patterns of psychiatric illness. This work was inspired by the work of Bowlby (2), whose book summarizes his own studies and those of others on this theme. He emphasized the need to define accurately a maternal separation experience. Many studies have noted relationships between a "broken home" and later mental illness or delinquency, but this concept was too loose a one for scientific purposes.Bowlby's studies and similar investigations have largely been concerned with children and adolescents, with one or two covering early adult life. We have been interested in the effect throughout life of early maternal deprivation. We have also investigated the fallacies which critics of Bowlby have pointed out, that is, the possibility that unstable parents with a hereditary burden of psychopathic factors have themselves produced the separation experiences of Bowlby's patients by means of divorce, separation, illegitimacy, admission to mental hospital, etc. Bowlby's conclusions were briefly that early maternal deprivation, if severe, would provoke later delinquency or sociopathic personality, and if less severe, a neurosis.

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biotics were given to them all as prophylactic treatment; the three that recovered also received either cortisone, blood transfusion, or a combination of blood transfusion and folic acid (other lines of treatment suggested in the textbooks are: "pentnucleotide," leucocytic cream, and pyridoxine).