Negative diffusivity and uphill diffusion, that contrast with Fick’s laws, however which can occur in multicomponent and single systems. In this paper, authors present studied results about the dynamics of the uphill diffusion in ternary and single system. Results have shown that: i) in ternary systems, the dynamics of negative diffusivity is high concentration effect and the combina-tion of coupled diffusion effect with high concentration effect is the dynamics of uphill diffusion; ii) in single systems, the difference of temperatures in two areas that is the dynamics of negative diffusivity and uphill diffusion. Keywords: Dynamics of uphill diffusion; dynamics of negative diffusivity.