Dental practice is the integral component of the oral health. Though the dental practice is in close relation with that of the medical practice, it has its own distinctiveness in relation to safe practice. The safe dental practice should not only assure good oral and general health but also improve social interaction by enhancing physical appearance, esthetics, etc. For the safe dental practice, dentists must excel in patient care and standard of treatment. The interlocking missions of education, research, and patient care are the cornerstones for the safe and healthy dental practice. This paper is designed to bridge the gap between the educational preparation of the dentist and the reality of the working world in a simple way.