Shoreline changes are crucial for assessing human-ecosystem interactions in coastal environments. They are a valuable tool for determining the environmental costs of socioeconomic growth along coasts. In this research, we present an assessment of shoreline changes along the eastern coast of Lahou-Kpanda of the Ivory Coast during the period from 1980 to 2020 by applying Digital Shoreline Analysis System method using Landsat Data Series. The measurement of the shoreline dynamics of the Lahou-Kpanda coastline is mainly described in three parts: the west straight cordon, the dynamics at the mouth and the east straight cordon. The findings show a drastic reduction in natural shorelines. The greatest transition occurred along the mouth segment of the coast, where the average erosive velocity approaches 90 meters each year and the average distance has decreased by around 2 kilometers. The Ivory Coast lost more than 40% of its biological shorelines between 1980 and 2020, according to this report, a worrying development because these are regions that were once biologically abundant and highly rich. In general, human operations on the Ivory Coast’s shorelines have never had such an impact. The effects of these changes on habitats, as well as the vulnerability of new shoreline investments to increased human activity and sea-level rise, must be measured.