Background
Evidence suggests that cervical cerclage should be offered to women after three or more previous preterm births (PTB) or second-trimester losses. Ultrasound-indicated cerclage reduces the rate of recurrent PTB in women with previous PTB or late miscarriage and a shortening cervix before 24 weeks. Patient selection is therefore critical for this intervention.
Aim
To assess the impact of a specialist antenatal service for women at risk of PTB on patient selection for cervical cerclage, cerclage rates and pregnancy outcome after surgery.
Methods
Women undergoing cervical cerclage were identified from the prospectively collected Anaesthetic Obstetric Procedure database and the PTB clinic database at University College London Hospital. Data on cervical cerclage and pregnancy outcomes were collected.
Results
There were 210 cases of cerclage; 85 cases before the PTB clinic was established (January 2005–December 2008), and 125 cases since (January 2009–December 2012). The rate of cerclage per 1000 women delivered fell from 6 to 5. Median gestational age at cerclage placement fell after establishment of the clinic (17+0/40, 13+2–23+3 to 15+2/40, 12+2–23+4 weeks). The proportion of rescue cerclages fell (26% to 12%) and the proportion of elective cerclages (history-indicated) doubled (44% to 88%). The median GA at delivery increased from 28+2/40 (17+0–39+5) to 35+2/40 (18+0–41+5).
Conclusion
The introduction of a specialist antenatal service for women at risk of PTB results in better patient selection for cerclage, earlier placement of cerclage, a reduction in rescue cerclages, and a lower rate of PTB and late miscarriage in those women who undergo surgery.
Fahdi BS. A case of craniopagus parasiticus: an antenatal diagnosis by ultrasound screening at 16 weeks of gestation and a literature review of recently reported cases. Turk J Pediatr 2019; 61: 941-945. Craniopagus parasiticus (CP) is a rare type of malformation of conjoined twins, with one degenerated or underdeveloped parasite twin united at the cranium with the other fully developed twin. Only a handful of cases have been documented in the literature to date. The incidence of this rare deformity is approximately 4 to 6 out of every 10,000,000 live births. We report on a case of CP, diagnosed at 16 weeks of gestation by ultrasound screening. To the best of our knowledge, the case that we present is the first CP case that was diagnosed at such an early gestational age. The formed fetus was found to harbour complex cardiac anomalies. In view of poor prognosis of survival after delivery and upon permission from the couple, the pregnancy was terminated at 17 weeks of gestation.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.