Radiation environment generates high soft error rates in conventional SRAM. To overcome this issue, several radiation hardened by design SRAM circuits (12TRHBD, 13TRHBD, DICE, etc.) have been developed. Although many of the radiation hardened SRAM cells are there, all the circuits mainly concern a single node upset only. In this chapter, 16T radiation hardened static random-access memory bit cell is designed and verified for a single node and multi-node upset. RHBD 16T bit cell is designed with SAED-PDK 32nm technology and compared with recently reported RHBD 12T and has a 99% improvement in recovery rate. Simulation results show that RHBD 16T is more resilient to a single node and multi-node upset. This shows that the proposed RHBD16T cell is highly tolerant against radiation strikes.