No abstract

La maladie de Takayasu (MT) est une artériopathie inflammatoire chronique touchant l´aorte, ses principales branches et les artères pulmonaires. Son appellation tient de l´ophtalmologiste japonais Mikito Takayasu qui publia en 1908 la première description de la maladie. Il s´agissait d´un patient de 78ans admis pour douleur abdominale, douleur du membre inférieur droit à la marche, insomnie. Evoluant depuis 1an sans antécédent de maladie cardio-vasculaire connu. A l´examen physique: le rythme cardiaque régulier à 87 battements par minute sans bruits pathologiques surajoutés avec une absence de pouls pédieux droit, tension artérielle à 120/78 mmhg, poumons libres, abdomen souple avec une masse battante dans la fosse iliaque droite dont l´auscultation met en évidence un souffle continu. Le reste de l´examen est sans particularité. L´angioscanner abdominal confirmait un aspect de dissection aortique étendue sur l´ensemble de l´aorte abdominale avec opacification synchrone des deux chenaux, un anévrisme thrombosé des artères iliaques primitives mesurant 48mm x100mm à droite et 38mm x 90mm à gauche, absence de fissuration visible. Nous rapportons le cas d´une dissection de l´aorte abdominale associée à un anévrisme thrombosé des artères iliaques primitives révélant une maladie de Takayashu au service de cardiologie de l´hôpital national Ignace Deen. La fréquence de la dissection de l´aorte abdominale au cours de la maladie de Takayasu est rare. Elle est plus souvent diagnostiquée dans sa phase occlusive. Le pronostic dépend des complications évolutives.

Atrial fibrillation is the most common heart rhythm disorder in humans. Al though it mainly affects the elderly, it can also be present in young people. In the absence of treatment, atrial fibrillation can have serious complications, including stroke or heart failure. The absence of an earlier study on AF before 50 years in Guinea, the multiplicity of etiologies motivated the present work with the objectives of determining the magnitude of AF before 50 years and identify the most common etiology. This was a prospective study that included 20 cases of atrial fibrillation in subjects under 50 years of age in the cardiac department of Ignace Deen National Hospital between 1st December 2017 and 30th June 2018. Included in this study were all patients under the age of 50, regardless of sex, who have an FA diagnosed on a resting electrocardiogram. During the study period 80 cases of FA were collected on 398 hospitalizations or a hospital frequency of 20.1% of which 20cas of FA in the subjects aged under 50 years were identified either a frequency of 5.02 %. The most frequent age group was 20 to 29 years old, ie 40% with the extreme age of 11 and 49 for a median age of 34.2 years. The female gender was predominant, 65% versus 35% of the male gender. Valvulopathies and pericarditis accounted for the most common etiologies (60% and 15%, respectively). Atrial fibrillation is not only the prerogative of the elderly. Before the age of 50, the etiology is dominated by valvulopathies because of the endemicity of rheumatic fever in our tropical environments.

Introduction: Heart and kidney diseases are common among patients admitted to hospital and they coexist in a significant number of cases. The interactions between the cardiovascular system and the kidney have been known and described for many years and have led to the description of cardio-renal syndrome. The objective of this study was to determine the frequency; to describe the clinical, etiological and prognostic aspects of acute renal failure in patients hospitalized for chronic congestive heart failure. Method: This was a descriptive retrospective study from January 2, 2018 to December 31, 2022. Included in this study were all the complete records of patients hospitalized for chronic congestive heart failure with serum creatinine ≥120 µmol/I. We're not included in this study, incomplete files, records of patients hospitalized for other pathologies, records of patients hospitalized for chronic congestive heart failure with normal renal function. Our study variables were qualitative and quantitative divided into clinical, paraclinical and prognostic data. Our data were analyzed using the EPI-info 7.2.2.6 software. Data entry and presentation were carried out using Word, Excel and PowerPoint from the 2016 Office Pack. Results: We collected 830 files of which 114 met our selection criteria, a frequency of 13.73%. The mean age of the patients was 47 ± 19 years. The F/M sex ratio was 1.23. The dominant etiologies were hypertension followed by diabetes with respectively 60.5% and 23.7%. Toxic factors including tobacco accounted for 7.9% of cases. Dyspnea accounted for 86.8%. Most of our patients were grade 3 or 36% based on systolic blood pressure on admission How to cite this paper:

Vaccination against COVID-19 is the most recognised means of containing the pandemic. Vaccines are not without side effects, particularly vascular thrombosis. But before blaming the vaccines, a thorough assessment of thrombotic risk factors is necessary. We report a case of arterial and venous thrombosis after vaccination with AstraZeneca revealing an exaggeration of factor VIII in a 37-year-old female patient. The angioscanner showed a venous thrombosis of the right subclavian, a pulmonary embolism and the presence of a thrombus in the aorta. The biology was in favour of a high level of factor VIII. The patient was treated with an antivitamin K, and the clinical evolution was favourable.