According to the WHO, health is a circumstances of personal resources. There is a necessity to prevent health related issues by diagnosing the disease within time. Number of hazardous diseases are there which are not able to catch within time. Globally from top ten diseases, one of the leading cause of death is tuberculosis. Due to the complicated structure, diagnose the bacteria of tuberculosis is very tedious job. Its an airborne disease. So there is a huge requirement to build a technique which can detect tuberculosis easily and at an early stage. The purpose of the paper is to study, design, and simulate the cantilever biosensor for quick detection of tuberculosis. Micro cantilever biosensor are designed with different dimensions and shapes. The surface of micro cantilever biosensor are prepared with various materials and are coated with antibodies. The sample of patient is placed on to the cantilever, if sample is infected with tuberculosis then antibodies get binds with antigens and it generate stress on the surface and it delivers displacement. Displacement of various designs of micro cantilever were analyzed and maximum displacement were recorded. Rectangle shape with gold material of micro cantilever biosensor achieved maximum displacement as 1.71 x 1028 µm for a load of 100N.

Mycobacterium Tuberculosis is one of the most hazardous disease. Universally millions of people are suffering from this dangerous disease. Number of detection techniques are available, but due to its complex structure this infectious disease not get diagnose easily and within time. To prevent spreading the bacteria and to stop mortality there is a huge requirement to build an automated and easy technique which can detect tuberculosis at a developing phase. The purpose of the article is to design and simulate the cantilever biosensor for detection of tuberculosis. Micro cantilever biosensor are designed with cylindrical and rectangular shape with silicon substrate. The cantilever surface is coated with antibodies and when patient sample is placed on it, the antigen-antibody gets binds together. When targeted antigen-antibody binds together stress generated and it forms deflection. The displacement achieved by Cylindrical-shape was 2.06 × 10 6 µm and rectangular-shape was 1.2 × 10 26 µm for 100N load force correlates to 28.228 × 10 -24 kg weight of antigen. From both the model maximum displacement were recorded and considered the rectangular-shape model as the leading model for tuberculosis detection.