No abstract

Acute myocardial infarction (MI) occurs when flow of blood to the heart is suddenly cut off, that lead to damage of the tissue. This is causing by a blockage in one or more of the coronary arteries. A blockage can expand due to a buildup of plaque, a substance mostly made of fat, cholesterol, and cellular waste products. Atherosclerosis may be a chronic inflammation disease and it is an active process, it is having mainly role in the MI pathogenesis, the inflammatory responsible for to accelerate atherosclerosis, decrease anti inflammation associated with MI, novel marker Adropin has anti inflammation and cardiovascular protective role. The objective of this study was evaluate Adropin levels in acute Myocardial Infarction and find the correlation between Adropin, and cardiac biomarker (hs-TI, hs-CRP and CKMB). The patients in this study were 50 patients and 50 control, when measurement of Adropin in studies groups of MI found that decrease in concentration of serum Adropin in patents groups of compare with control. The conclusion was that Adropin can be used to diagnose acute myocardial infarction, along with the use of a Cardiac biomarker such: (hs-TI), (hs-CRP) and Creatine kinase (CK-MB).