Background: Sputum smear negative tuberculosis can be a diagnostic challenge and there can be a dilemma in initiation of treatment, CBNAAT is one important test which gives quick results within hours plus an additional information about resistance with rifampicin, in sputum negative or nonexpectorating patients brochoalveoloarlavagae can be useful, if tested for CBNAAT made available via fiberoptic bronchoscopy. Materials and Methods: Clinico-radiological suspects of pulmonary tuberculosis who showed clinical symptoms and radiological opacities consistent with tuberculosis who were sputum negative or not expectorating sputum were included in this study with exclusion patients in whom bronchoscopy was contraindicated, smear and CBNAAT examination was done of the obtained sample. The data was then analyzed. Results: in our study of 100 patients 57 were males and 43 were females, the most common lesion detected in imaging was consolidation 44% of patients followed by cavitary lesions at 27 %. Out of 100 patients who were clinicoradiologically suspected for PTB who underwent bronchoscopy 45 were diagnosed PTB out of which 32 tested positive for CBNAAT, no rifampicin resistance was detected in those cases. Conclusion:CBNAAT obtained from broncho-alveolar samples can be of great value especially when there is a physicians dilemma to start antitubercular treatment, as there are also other conditions mimicking tuberculosis both radiologically and clinically. Hence, BAL results with CBNAAT can help to arrive at a conclusion.

No abstract

Tropical pulmonary eosinophilia (TPE) is a specific pulmonary manifestation of lymphatic filariasis. There is overwhelming infiltration of eosinophils in the lung parenchyma in response to microfilaria. The characteristic features include paroxysmal respiratory symptoms, strikingly high blood eosinophil count, elevated level of immunoglobulin (Ig) E along with high titer of anti-filarial antibody. Treatment with diethylcarbamazine (DEC) has an excellent favorable response. However, recovery may often be incomplete.We present a case of a 36-year-old man with TPE who had complete symptomatic improvement after a three-week course of DEC, but only a partial response in radiological and pulmonary function abnormalities.

Background: Tuberculosis is considered as one of the most reason for death worldwide including India. In India, population, destitution, lack of healthy sustenance, and profoundly blocked climate may help for disease with Mycobacterium tuberculosis. The finding and treatment of tuberculosis in not in appropriate with regular strategies. Here we analyzed the location of M. tuberculosis with two traditional strategies. Materials and Methods: This study was completed to compare and conclude about outcome between the traditional AFB (Acid Fast Bacilli) microscopy and Lowenstein-Jensen (LJ) culture strategy for recognition of Mycobacterium spp. in sputums from patients. Results: Among 100 examples, 57 (57%) AFB+ results were seen in microscopy with ZN stain. On LJ culture media, 62 (62%) AFB+ detaches were discovered which uncovers that the way of life could be a highest quality level for conclusion of TB. Conclusion:The AFB smear is fast, modest and explicit test for early finding of TB however Its affectability is low when contrasted with refined strategy in LJ medium which is the gold standard for the confirmation of tuberculosis.