For surgical treatment, herniation of traditional open surgery is the traditional approach and the representative operation for lamina windowing excision of nucleus pulposus. In recent years, the unilateral dual channel spine endoscopic technology (UBE/BESS) has caused extensive concern of spine surgery performer. This research compared the results of minimally invasive percutaneous treatment of severe lumbar disc herniation with foraminal single-channel endoscopy and unilateral biportal endoscopy (UBE). A retrospective study was conducted on 50 patients with severe disc herniation treated with minimally invasive percutaneous treatment in MinDong Hospital affiliated to Fujian Medical University from September 2019 to September 2021. According to different surgical methods, they were divided into two groups: foraminal single-channel endoscopic group and UBE dual-channel endoscopic group. There were 22 cases in the UBE surgery group and 28 cases in the interforaminal endoscopic group. The comparison included operation time, postoperative hospital stays, preoperative and postoperative pain scale (VAS), and postoperative MRI to observe the residual condition of prolapsed nucleus pulposus and the occurrence of complications. There were no significant differences between the UBE group and the interforaminal endoscopic group in incision length, operation time, postoperative hospital stays, and improvement of VAS score before and after surgery. In terms of postoperative nucleus pulposus residual rate and postoperative recurrence rate, the two-channel UBE group was significantly better than the single-channel interforaminal endoscopic group. The incidence of postoperative anemia in the interforaminal endoscopic group was significantly lower than that in the UBE group. In the treatment of severe disc herniation, UBE two-channel endoscopy has the advantages of lower recurrence rate, lower nucleus pulposus residual rate, shorter learning curve, and better field of vision than foraminal single-channel endoscopy, which is worth promoting in primary hospitals.

This study investigated the nanohydroxyapatite (nHA) prosthesis application effect based on CT-scanning data in spinal injury. This study chose 26 spinal injury patients treated in our hospital from September 2017 to September 2018, who were randomly divided into two groups. nHA prosthesis based on CT-scanning data was implanted in the nHA group, whereas titanium mesh was implanted in the titanium mesh group. Consequently, osteoblasts were cultured to test the biological activity of nHA and titanium alloy. In cell tests, we found osteoblasts could better adhere to nHA, and proliferation and activity were higher when planted on nHA material. After surgical treatment, all patients’ spinal symptoms (VAS score, JOA score, and Cobb angle) had improved and did not cause obvious inflammatory foreign body reactions. During a two-year follow-up, the fusion time and support settlement in the nHA group was lower, and the vertebral fusion rate and ASIA score were higher than those in the titanium mesh group. Thus, CT-scanning data could further improve the vertebral fusion rate in the nHA group. Consequentially, nHA prosthesis based on CT-scanning data is a better choice for spinal injury therapy.