Jasmonic acid (JA) is an important phytohormone in optimizing plant developmental growth and stress responses. The biosynthesis and signalling pathways of JA share common and unique features between herbaceous and woody plants. However, numerous reports have primarily focused on JA function in model plant species or herbaceous plants, leading to a notable lack of research on the JA regulatory mechanism in woody plants. In particular, the role of Jas in posttranscriptional regulation events such as alternative splicing (AS), has largely not been elucidated in trees. In this review article, we summarize the current progress of JA-involved regulation of developmental growth in different tree species. Along with an accumulating number of studies revealing that AS participates in the JA regulatory network in woody plants, we also update the multiple roles served by JA associated with similar properties and differential regulation within their herbaceous counterparts. The utilization of genetic studies and high-throughput proteogenomic approaches to analyse AS genes and splicing factors involved in JA signalling would further advance our understanding of JA modulation in woody plants.

The gene SYF2—an RNA splicing factor—can interact with Cyclin D-type binding protein 1 (GICP) in many biological processes, including splicing regulation, cell cycle regulation, and DNA damage repair. In our previous study we performed genome-wide identification and functional analysis of SYF2 in plant species. The phylogenetic relationships and expression profiles of SYF2 have not been systematically studied in animals, however. To this end, the gene structure, genes, and protein conserved motifs of 102 SYF2 homologous genes from 91 different animal species were systematically analyzed, along with conserved splicing sites in 45 representative vertebrate species. A differential comparative analysis of expression patterns in humans and mice was made. Molecular bioinformatics analysis of SYF2 showed the gene was conserved and functional in different animal species. In addition, expression pattern analysis found that SYF2 was highly expressed in hematopoietic stem cells, T cells, and lymphoid progenitor cells; in ovary, lung, and spleen; and in other cells and organs. This suggests that changes in SYF2 expression may be associated with disease development in these cells, tissues, or organs. In conclusion, our study analyzes the SYF2 disease resistance genes of different animal species through bioinformatics, reveals the relationship between the SYF2 genotype and the occurrence of certain diseases, and provides a theoretical basis for follow-up study of the relationship between the SYF2 gene and animal diseases.

Introduction: Osteoarticular infections caused by Salmonella spp. are rare. Salmonella osteomyelitis is more common in children with underlying chronic diseases or immunodeficiency, but is rare in previously healthy children. Patient concerns: Six previously healthy children with Salmonella osteoarticular infections were admitted to our hospital. Identification and characterization of the isolates were also performed and correlated with the clinical findings. Diagnosis: The predominant symptoms were fever, pain, and swelling. Three patients were diagnosed with osteomyelitis (including 2 with left humerus, 1 with left tibia), 1 patient with osteoarthritis (elbow, right), and 2 patients with septic arthritis (knee joint, right). Interventions: Surgical drainage was performed in all children, and the aspirates were subsequently cultured. Intravenous antibiotic therapy combined with surgical drainage of purulent material is necessary to eradicate the infection. Outcomes: A 2-year follow-up showed good healing in all six children after clinical interventions. Conclusion: Osteoarticular infections caused by Salmonella have no distinctive features, clinical manifestations, or radiological characteristics. Intravenous antibiotics combined with surgical debridement/drainage are necessary for eradication of the bacteria.