To cite this version:J Riegler, B Allain, R J Cook, M F Lythgoe, Q A Pankhurst. Magnetically assisted delivery of cells using a magnetic resonance imaging system. Journal of Physics D: Applied Physics, IOP Publishing, 2011, 44 (5) AbstractA simple analytical model is presented which enables rapid interactive prediction and control of magnetically labelled cells in an arterial bifurcation using magnetic field gradients produced by a magnetic resonance imaging system (MRI). This model is compared against experimental results for human mononuclear cells labelled with micron sized superparamagnetic iron oxide particles. Experimental and theoretical results highlight the importance of cell aggregation for magnetic targeting in a strong magnetic field. These predicted aggregates are confirmed via confocal endoscopy which allows the visualisation of cell aggregates and their movement inside a vascular flow model in a 9.4T preclinical MRI scanner.

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Tracking biopsy sites in endoscopic images can be useful to provide a visual aid for the guidance of surgical tools, for example when endoscopic guided biopsy is required. A new method for re-localisation of these sites is presented in this paper. It makes use of epipolar geometry properties between three images of the same site observed from different viewpoints with an endoscope. Two epipolar lines are derived from the two first images in the third image where the site needs to be re-localised. Their intersection corresponds to the location of the biopsy site. This method was tested with gastroscopic data from 2 patients with 9 series of three images of the oesophagus. The re-localisation error was estimated at less than 1.5 millimetres by a clinical endoscopist, which is sufficient for most clinical endoscopic applications.