This article introduces a new qualitative-quantitative approach to assess meaning of life. The participants described their sources of meaning and how they were interconnected. Four quantitative measures for (1) the accessibility of meaningrelated knowledge, the degree of (2) differentiation and (3) elaboration of personal meaning systems, and (4) their coherence were calculated. The sample consisted of 59 theology and science students. The study tested (a) whether the structural properties of personal meaning systems predicted health and well-being, and (b) reflected different degrees of expertise in constructing meaning. Differentiation, elaboration, and coherence measures correlated with health and well-being and predicted life satisfaction. Theology students presented more differentiated, elaborated, and coherent personal meaning systems than science students. Both results indicate that assessing structural properties of personal meaning systems can be a promising new approach to measure meaning of life.

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