Introduction: Food allergy is a chronic disease that requires a great deal of effort. It can result not only in a reduced quality of life, but also increased feelings of anxiety and stress. This study examines the association between health-related quality of life (HRQL) and trait anxiety levels in adults with food allergy. Methods: The research sample consisted of 167 adults with food allergy aged 19-69 years, arithmetic average (M) age 37. The STAI X2 questionnaire was used to measure trait anxiety. The food allergy quality of life questionnaire for adult population (FAQLQ-AF) was used to measure the health-related quality of life -and this achieved high reliability values. Results: A moderate, positive relationship was demonstrated between anxiety and the FAQLQ-AF. Simple linear regression analysis demonstrated that trait anxiety level is a predictor of HRQL level, and an increase in anxiety level decreases HRQL. Factors such as tetanus syndrome, comorbidities, prescribed medications and recommended over-the-counter medications are associated with trait anxiety levels. Related illnesses and symptom clusters are related to HRQL levels. Conclusions: Adults with food allergy who are more anxious are more likely to experience a poorer quality of life. Early intervention, prevention and optimization of treatment management should be a necessary part of the psychological care of patients with food allergy.