In December 2019, the Chinese city of Wuhan was the center of origin of a pneumonialike disease outbreak with an unknown causative pathogen. The CDC, China, managed to track the source of infection to a novel coronavirus (2019-nCoV; SARS-CoV-2) that shares approximately 79.6% of its genome with SARS-CoV. The World Health Organization (WHO) initially declared COVID-19 as a Public Health Emergency of International Concern (PHEIC) and later characterized it as a global pandemic on March 11, 2020. Due to the novel nature of this virus, there is an urgent need for vaccines and therapeutics to control the spread of SARS-CoV-2 and its associated disease, COVID-19. Global efforts are underway to circumvent its further spread and treat COVID-19 patients through experimental vaccine formulations and therapeutic interventions, respectively. In the absence of any effective therapeutics, we have devised h bioinformatics-based approaches to accelerate global efforts in the fight against SARS-CoV-2 and to assist researchers in the initial phase of vaccine and therapeutics development. In this study, we have performed comprehensive meta-analyses and developed an integrative resource, "CoronaVR" (http://bioinfo.imtech.res.in/manojk/ coronavr/). Predominantly, we identified potential epitope-based vaccine candidates, siRNA-based therapeutic regimens, and diagnostic primers. The resource is categorized into the main sections "Genomes," "Epitopes," "Therapeutics," and Primers." The genome section harbors different components, viz, genomes, a genome browser, phylogenetic analysis, codon usage, glycosylation sites, and structural analysis. Under the umbrella of epitopes, subdivisions , namely cross-protective epitopes, B-cell (linear/discontinuous), T-cell (CD4 + /CD8 +), CTL, and MHC binders, are presented. The therapeutics section has different subsections like siRNA, miRNAs, and sgRNAs. Further, experimentally confirmed and designed diagnostic primers are earmarked in the primers section. Our study provided a set of shortlisted B-cell and T-cell (CD4 +
This article attempts to examine the behaviour of various sectors, with emphasis on the role of income inequality. First, the article estimates the sectoral decomposition in terms of net state domestic product (NSDP) among different states from years 1991–1992 to 2016–2017. Second, we analyse the sector-wise decomposition of regional inequality in term of per capita income. Finally, we analyse the role of developmental expenditure in regional inequalities in term of per capita developmental expenditure across various states. Based on empirical results, India has witnessed a high growth in per capita income in the post-reform period. With high growth rate, the sectoral composition of income has also registered a major change. The tertiary sector is the major contributor to growth in the post-reform period. At the sectoral level, disparity decreased within the sectors in case of primary and tertiary sector and increased in secondary sector. However, overall, the tertiary and secondary sectors are more responsible for raising the income inequality among the states while primary sector is offsetting this gap. JEL: O15, I14, I32, O12
The literature of war exposes the gender binaries and stereotypes that are reinforced by war. The Vietnam War is one of the most popular wars in American history; it is the first war televised live. The reason for its popularity lies in its project of ‘re-masculinizing’ America. With the Cold War and the Anti-War protests all over the country, America used the gender norms to justify the war. Of its multi-layered gender role enforcement, first it projects itself as the masculine ‘saviour’ who is going to fight for democracy and rights of a ‘feminized’ Asian country; second, its use of misogynistic slangs to create a homo-social bond among men and alienate women; but can the presence of women be omitted? In my paper I shall do a close textual analysis of The Things They Carried by Tim O’Brien to show how he explores the female presence in the Vietnam War, as well as how the novel is a critique of the war literature of the time that attempts to reinforce the gender binaries.
The fashion industry has become more globally competitive as a result of increased globalisation. The recent introduction of new technologies has presented opportunities as well as obstacles for the fashion industry, especially for small and medium-sized businesses (SMEs) whose low resources may make it difficult for them to adopt new technology. But, with the rise of social media, fashion SMEs have new opportunities that can help them become more visible and boost their sales. Accordingly, the present study attempts to analyse the efficacy of social media usage on the performance of SMEs in fashion industry. The study will use both qualitative and quantitative approach to examine the social media usage in terms of reach, richness, affiliation, and influence on SMEs performance. Data will be collected from 400 SMEs in Delhi through questionnaire and their respective social media account (Facebook). Results of the study show that most of the small and medium-sized enterprises used social media for business purpose, and their performance is improved after using social media.
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