Constant research work and evidences over the years indicate that consumption of tea, especially green tea, is good for preventing cancer. A growing body of evidence suggests beneficial role of green tea and its polyphenol in oral cancer. To elucidate the cancer preventive mechanisms of green tea, much effort has been devoted to investigate the anticancer effects of Epigallocatechin-3-gallate (EGCG), the major catechin of green tea. It has been revealed that EGCG restrained carcinogenesis in a variety of tissues through inhibition of growth factor-related cell signaling, reducing inflammatory mediators such as COX-2 and thereby limiting bioactivity of PGE2. It also enhances gene expression, modulates cellular proliferation and apoptosis. EGCG is a multi-potent anticancer agent, which not only provides solid evidence to support the anticancer potential of green tea, but also offers new ways for discovering multiple-targeted anticancer drugs.

Osteomyelitis is an inflammatory bone disease commonly related to an infectious origin. Osteomyelitis was relatively common before the era of antibiotic therapy. Today osteomyelitis of facial bones is a rare condition. Maxillary osteomyelitis is rare compared to mandiblar osteomyelitis because extensive blood supply & strut like bone of the maxilla make it less prone to chronic infection. A 70 year old female presented to us with pus discharge from left maxilla following dental extraction with offensive odour. Examination revealed a necrotic maxilla on the left side with pus disharge. A computed tomography scan confirmed Osteomyelitis of left Maxilla. Patient underwent surgical excision. Satisfactory results were obtained with appropriate antibiotics and surgical excision. Adult Osteomyelitis remains one of the most difficult-to-treat infectious diseases, with considerable morbidity and costs to the health care system. Osteomyelitis is now such a rare entity that when presented, the possibility of underlying pathology should be considered and appropriately investigated for.

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