Low-field permanent magnet-based MRI systems are finding increasing use in portable, sustainable and point-of-care applications. In order to maximize performance while minimizing cost many components of such a system should ideally be designed specifically for low frequency operation. In this paper we describe recent developments in constructing and characterising a low-field portable MRI system for in vivo imaging at 50 mT. These developments include the design of i) high-linearity gradient coils using a modified volume-based target field approach, ii) phased-array receive coils, and iii) a battery-operated three-axis gradient amplifier for improved portability and sustainability. In addition, we report performance characterisation of the RF amplifier, the gradient amplifier, eddy currents from the gradient coils, and describe a quality control protocol for the overall system.

In this paper we design and construct gradient coils for a Halbach permanent magnet array magnetic resonance (MR) scanner. The target field method, which is widely applied for the case of axial static magnetic fields, has been developed for a transverse static magnetic field as produced by a Halbach permanent magnet array. Using this method, current densities for three gradient directions are obtained and subsequently verified using a commercial magneto-static solver. Stream functions are used to turn the surface current densities into wire patterns for constructing the gradient coils. The measured fields are in good agreement with simulations and their prescribed target fields. Three dimensional images have been acquired using the constructed gradient coils with very low degree of geometric distortion.

Objective Low-cost low-field point-of-care MRI systems are used in many different applications. System design has correspondingly different requirements in terms of imaging field-of-view, spatial resolution and magnetic field strength. In this work an iterative framework has been created to design a cylindrical Halbach-based magnet along with integrated gradient and RF coils that most efficiently fulfil a set of user-specified imaging requirements. Methods For efficient integration, target field methods are used for each of the main hardware components. These have not been used previously in magnet design, and a new mathematical model was derived accordingly. These methods result in a framework which can design an entire low-field MRI system within minutes using standard computing hardware. Results Two distinct point-of-care systems are designed using the described framework, one for neuroimaging and the other for extremity imaging. Input parameters are taken from literature and the resulting systems are discussed in detail. Discussion The framework allows the designer to optimize the different hardware components with respect to the desired imaging parameters taking into account the interdependencies between these components and thus give insight into the influence of the design choices.

In this work a low field point-of-care system design framework is created using target field methods for all of the hardware components. A new target field method for Halbach-based magnet optimization with variable ring diameter and spacing is derived. Magnet, gradient and RF are combined into a single framework which includes a feedback loop for dealing with the component interdependencies. The result is a pipeline which with a few user inputs can create an optimal magnet, gradient and RF design in minutes.