Background: Many antineoplastic agents are known to be teratogenic and mutagenic to humans. Nurses are the main groups that are exposed to these drugs in hospital setting. Generally, the occupational activities that pose to greatest risk of exposure are the preparation and administration of antineoplastic agents, cleaning of chemotherapy spills, and handling of patient excreta. Objective: The objectives of this study were to evaluate the knowledge of nurse regarding the way of exposure of Cytotoxic Drugs (CDs) and to determine the current patterns of use of personal protective equipments while handling antineoplastic chemotherapeutic agents. Methods: An analytic cross sectional study was carried out at BPKIHS Dharan. The study was carried out on 125 nurses. The random sampling technique was used to select the study subjects using structured and semi-structured questionnaire. Collected data were analyzed using descriptive and inferential statistics. Result: More than 92% of participants reported usually wearing gloves during chemotherapy handling; 6% reported using laboratory coats as protective garments. Usual use of face and respiratory protection was less than 5%. Chemotherapy was reported to be prepared in nursing station where there are no laminar airflow hoods in 100% of work settings. None of the subjects have reportedly provided any type of medical monitoring. Conclusion: Use and availability of gloves have increased but personal protective equipment like protective garments, face and respiratory protective, when handling chemotherapy have decreased and medical monitoring of exposed employees still is neither widely practiced nor consistent with Occupational Safety and Health Administration (OSHA) guidelines

Background: Incorrect drug dose calculations by nursing students can cause drug errors and harm patients. Their ability to calculate the correct dosage of drugs consistently need to be evaluated regularly. The objective of the study was to evaluate the drug dose calculation ability of nursing students.Methods: A pre-post interventional study was conducted among 99 undergraduate nursing students studying in 2nd, 3rd and 4th year. Pre-test was conducted using a 20-item self-administered questionnaire on drug dose calculation test followed by a 30 minute lecture on the methods of drug dose calculation. Post-test was conducted using the same questionnaire after a washout period of six weeks. Mean score, standard deviation, frequency and percentage were calculated. Student t test, one way ANOVA and McNemar Test were used for statistical analysis using SPSS version 11.5 at P-value of 0.05.Results: Pre-test and post-test mean score were 10.59 ± 3.00 and 15.36 ± 2.46 respectively. There was 45.04% increase in mean score in the post-test after the intervention and it was statistically significant (P-value < 0.05). None of students scored more than 90% of mastery level in the pretest and 42 students (42.4%) scored more than 90% of mastery level in the post-test. The mean score was highest for third year students in both pre-test and post-test; however, it was statistically not significant (P-value > 0.05).Conclusions: Drug dose calculation ability of the students was poor in the pre-test and it significantly improved after the intervention. The study findings highlight the need for regular continuing mathematical and drug dose calculation practice among the students.

The objective of the study was to evaluate the drug dose calculation ability of nursing students. A pre-post interventional study was conducted among 99 undergraduate nursing students studying in 2 nd year, 3 rd year and 4 th year. Pre-test was conducted using a self-administered 20-item questionnaire on drug dose calculation test followed by a 30 minute lecture on the methods of drug dose calculation. Post-test was conducted using the same questionnaire after a washout period of six weeks. Mean score, standard deviation, frequency and percentage were calculated. Student's t-test, one way ANOVA and McNemar Test were used for statistical analysis using SPSS version 11.5. P-value less than 0.05 was considered statistically significant. Pre-test and post-test mean score (± Standard deviation) were 10.59 ± 3.00 and 15.36 ± 2.46 respectively. There was 45.04% increase in mean score in the post-test after the intervention and it was statistically significant (P-value < 0.05). None of students scored more than 90% of mastery level in the pretest and 42 students (42.4%) scored more than 90% of mastery level in the post-test. The mean score was highest for third year students and lowest for 2 nd year students in both pre-test and post-test; however, it was statistically not significant (P-value>0.05). Drug dose calculation ability of the students was poor in the pre-test and it significantly improved after the intervention. The study findings highlight the need for regular continuing mathematical and drug dose calculation practice among the students.

To increase the maximum productivity is prime aim in fish aquaculture from past few years. The increase in maximum standing crop of a pond depends upon the wider range of available foods in ecological niches from the selection of complementary species growing together. The present work was conducted in an attempt to identify the suitable fish species combinations among Hypophthalmichthys molitrix, Aristichthys nobilis, Ctenopharyngodon idella, Cyprinus carpio with the introduction of Amblypharyngodon mola in the prevalent method of fish polyculture system practiced in Nepal. The experiment was conducted for 120 days, in twelve 100 m2 earthen ponds which comprised the initial growing period of fish. As control, one pond was stocked with a species ratio usually employed in the country; H. molitrix (35 %), A. nobilis (10 %), L. rohita (15 %), C. mrigala (10 %), C. idella, (5 %) and C. carpio (25 %). Treatment 2 was stocked with the H. molitrix, A. nobilis, L. rohita and C. mrigala. Treatment 3 was stocked with the H. molitrix, A. nobilis, L. rohita, C. mrigala and C. idella and Treatment 4 was stocked with the H. molitrix, A. nobilis, L. rohita, C. mrigala and C. idella and C. carpio. Each treatment had three replicates. Carp fishes were stocked with stocking density 15000 ha -1 in all treatments. A. mola was stocked @ 50000 ha-1 in treatments, 2, 3 and 4. No significant correlation was found between the growth rate of fish species and the water quality parameters. The final weight of different species, in different treatments, showed statistical differences. Considering growth parameters, the best result was obtained in treatment 2. A complete exclusion of the A. mola in treatment 1 had no advantage over the other treatments; however, the combination of Hypophthalmichthys molitrix, Aristichthys nobilis, Labeo rohita and Cirrhinus mrigala allowed the introduction of A. mola, with positive effects. In addition, the introduction of A. mola in the polycultures tested had no effect over the other carp species. Journal of Institute of Science and TechnologyVolume 22, Issue 2, January 2018, Page: 92-102

Introduction: The modality and quality of care received during hospitalization affects a child’s response to their illness. Thus, any intervention delivered by healthcare providers including nurses must be based on principles of atraumatic care. This study aims to assess the knowledge and attitude of nurses in the implementation of atraumatic care among hospitalized children in a tertiary care center in Eastern Nepal. Methods: A descriptive cross-sectional study was conducted among 106 nurses in a tertiary hospital from 4th January to 1st February 2020. Ethical approval was received from the Institutional Review Committee. Sampling was done by total population enumeration method. Data was collected using a self-administered three-part questionnaire and analyzed using Statistical Package for the Social Sciences version 11.5 by utilizing descriptive statistics. Results: The mean knowledge and attitude of nurses towards implementation of atraumatic care among hospitalized children was found to be 14.90 ± 3.90 and 74.74 ± 7.5 respectively. Out of 106 nurses, 73 (68.90%) had adequate knowledge whereas 56 (52.80%) had favorable attitudes towards principles and implementation of atraumatic care, assessed using reliable scales. Variations due to socio-demographic and professional parameters were insignificant. Conclusions: The study shows that majority of the surveyed nurses had adequate knowledge of the principles of atraumatic care and a favorable attitude towards its application among hospitalized children. However, the measured attitude of nursing practitioners was relatively lower in terms of favorability.