Facile and fluoride-free fabrication of high-throughput superhydrophobic materials to achieve efficient separation of oil/water mixtures is of great significance. A superhydrophobic copper mesh (SHCM) was synthesized by constructing copper hydroxide nanoneedles on a copper mesh via chemical oxidation followed by further modification with trichloromethylsilane. The band-shaped nanoneedles on the very top were interwoven to form a uniformly distributed array of silicone spots, resulting in a hierarchical surface structure. The synthesized SHCM possessed a static water contact angle (WCA) of up to 159°with good superoleophilic properties. The SHCM was applied for the separation of various oil/water mixtures, and the separation efficiency was up to 99.9% with extremely high oil fluxes of over 220 kL•m −2 h −1 . In addition, the excellent separation efficiencies and high throughputs of SHCM could be maintained with slightly lowered WCAs even after 80 separation cycles and a particle impact abrasion test. Using a self-designed netlike oil skimmer equipped with a SHCM, the floating oil on water could be easily collected. The SHCM synthesized in this study using a facial synthetic strategy has great potential in the application of actual oil/ water separation.