Thalassemia patients are at high risk of iron-induced toxicity and oxidative stress consequences. The present cross-sectional study is conducted to determine whether or not lipid peroxidation or protein oxidation is correlated with iron parameters in patients with thalassemia major. To prove this hypothesis, malondialdehyde and total carbonyl were correlated with the degree of excess iron concentration in the patients. A total of 118 Arabic Iraqi patients and 30 healthy children were participated in the present study. Results showed a significant increase (p<0.05) in serum total carbonyls, malondialdehyde and the iron indices of patients as compared with the control group. Total iron binding capacity and transferrin concentrations decreased significantly (p<0.05) in patients with thalassemia compared with the control group. The results also showed a lack of a significant correlation between each serum malondialdehyde and total carbonyl with each component of iron status. In conclusion, total carbonyls and malondialdehyde were increased in thalassemia patients indicating the vulnerability of these patients to tissue injury caused by oxidative stress. The formation of total carbonyl and malondialdehyde are independent of excess non-labile iron concentration, indicating that different mechanisms are involved in injury caused by the labile iron and in the formation of oxidation end products.

About 12,000 chemical compounds isolated from medicinal plants and used to conduct crucial biological functions. These phytochemicals offer long-term health benefits for humans, thus they can be used effectively for treat a variety of human ailments. The goal of this study was to assess the in vitro free radical scavenging and antibacterial activities of glycoside, flavonoid and alkaloid extracts of Tilia cordata plant.  According to the findings, flavonoid extract exhibits strong inhibitory action against Staphylococcus aureus but no activity against Escherichia coli. The free radical scavenging activity exhibited that the flavonoid extract was more effective in inhibiting lipid peroxidation more than alkaloid extract, whereas the glycoside extract had no antioxidant activity.

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The kidneys are important organs similar in shape to beans located on both sides of the spine and their function is to filter water and toxic substances from the blood. The kidneys, like other members of the human body, are exposed to failure due to many factors that ultimately lead to kidney damage. About five millimeters of one hundred samples from dialysis patients were kept in test tubes designated for this purpose, where the samples were stored at appropriate temperature until the required number was completed, the same measures were also taken on the healthy group, which numbered fifty samples, and their ages were approximately equal to the ages of the dialysis patients. As for the results of the current research, it was proved that there was a significant increase in the levels of zonulin and the capacity of total antioxidants, urea, creatinine and glucose in dialysis patients compared to the control group. As for glutathione, there is no significant change.