We describe a capacitance sensor array that has been incorporated into a lab-on-CMOS system for applications in monitoring cell viability. This paper presents analytical models, calibration results, and measured experimental results of the biosensor. The sensor has been characterized and exhibits a sensitivity of 590 kHz/fF. We report results from benchtop tests and in vitro experiments demonstrating on-chip tracking of cell adhesion as well as monitoring of cell viability. Human ovarian cancer cells were cultured on chip, and measured capacitance responses were validated by comparison with images from photomicrographs of the chip surface. Analysis was performed to quantify cell proliferation and adhesion, and responses to live cells were estimated to be 100 aF/cell.

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We report a low cost mobile EEG system for characterizing cortical auditory responses. The system is built using commercial off-the-shelf components and each unit costs less than $200. It measures seven EEG channels plus one audio channel (envelope only), and communicates the data to external devices via Bluetooth. A novel implementation was pursued in order to support local signal compression using compressed sensing. At the same time, it provides a low cost solution that is useful for recording cortical auditory responses and extracting clinically relevant features of the waveform. This system has been designed with the eventual goal of long term monitoring of the brain activity of schizophrenic patients outside a clinical setting, in order to better understand auditory hallucinations and manage their ongoing treatment. In this preliminary study we obtained simultaneous audio and cortical recordings of evoked auditory responses from normal healthy subjects wearing the EEG for several hours in duration. We report evoked auditory responses for 2 Hz and 40 Hz click trains. We also report alpha wave responses, demonstrating stable and high quality recordings over a five hour period

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