Background: Breast cancer is one of the most common cancers in females. Fine needle aspiration cytology plays an important role in the management of these patients. Aims and objectives: 1) To study Robinson's cytological grading on preoperative FNAC smears in cases of breast carcinoma. 2) To correlate Robinson's cytological grading with modified Scarff Bloom Richardson histopathological grading. Methods: A retrospective study was done on 50 patients of breast carcinoma over the period of 2 years from 1 st January 2018 to 31 st December 2019 at a tertiary care center. Results: Groups II and group III cases of breast carcinomas were correlated very well on cytological and histopathological grading. The sensitivity of cytological grading in the present study were 66.66%, 75% and 85.71 respectively. Specificity were 85%, 76.92% and 90.90% respectively i.e. maximum in grade III. The k value for present study showed 0.62 i.e substantial agreement. Conclusion: Cytological grading of breast carcinomas is a useful prognostic marker in the management of breast carcinoma. It is helpful in selecting the patients for modified radical mastectomy with axillary dissection and neoadjuvant chemotherapy.

Introduction: Ring-enhancing lesions is the most common abnormality faced in neuro-imaging. Imaging modalities commonly used to diagnose such lesions are Computed Tomography (CT) and MRI. However, these lesions are considered challenging for the radiologists. Diagnosing ring enhancing lesions by conventional MRI is challenging, especially when neoplastic, non-neoplastic lesions and infections are to be differentiated. Differentiation between tuberculoma and neurocysticercosis is still a problem for radiologist as both look similar on conventional MRI. Magnetic resonance spectroscopy (MRS) may able to clearly differentiate them based on metabolite level. Present study was conducted to study characteristics of various ring enhancing lesions of brain using conventional MRI and magnetic resonance spectroscopy (MRS) to differentiate neoplastic, infections, inflammatory and vascular lesions Materials and Methods: 50 patients between age 10 to 70 years diagnosed with ring enhancing lesions of brain based on MR studies fulfilling inclusion and exclusion criteria were enrolled. MRI scan was performed using the MRI GE optima 360-16 channel in all. Single voxel magnetic resonance spectroscopy (MRS) used instead of multi-voxel which was placed on the lesion in a way that the maximum area of the lesion, its margin and the normal brain tissue will be covered. Observations and Results: Primary Brain Tumors found in 16 (32%) cases, Metastasis in 22 (44%), Abscess in 8 (16%), Neurocysticercosis (NCC) in 2 (4%), Tuberculoma in 1 (2%) & Tumefactive Demyelination in 1 (2%) case. In majority of cases i.e. 38 (76%) size of the lesion was <2 cm. In about 26 (52%) cases number of lesions were 2 to 4 in number. Restriction on diffusion was found in 29 (58%) cases. In majority choline 26 (52%) & lipid 24 (48%) was the metabolite peak found Conclusion: Magnetic Resonance Spectroscopy (MRS) was found a useful tool in the diagnosis of ring enhancing lesions especially in case of delineating lesions with similar presentations such as tuberculoma and neurocysticercosis.

Background: In recent past image guided fine needle aspiration cytology of ovarian masses is being used for the pre-operative diagnosis of neoplastic ovarian lesions, The imaging may be in the form of routinely performed ultrasonography and fine needle aspiration cytology is done from the solid component of lesion. Material and Methods: A prospective study was conducted at our tertiary care center over the period of two years. The 32 patients with ovarian masses encountered. The sensitivity, specificity and diagnostic accuracy of FNAC was calculated. Pitfalls and limitations of cytological evaluation and histopathological diagnosis has been highlighted. Results: The sensitivity of fine needle aspiration cytology in this study is 81.81%, Specificity is 95.23% and diagnostic accuracy is 90.60%. Conclusion:The Ultrasonography guided FNAC is less invasive, economic, rapid diagnostic mode of early evaluation of benign and malignant ovarian tumors and helps in early management.

Lung cancer is one of the most common cancer worldwide and the leading cause of cancer‑related death. Needle biopsies of lung have been used for diagnosis of lung lesions. They are done CT guided or thoracoscopic guided procedures in our institution. The aim is to study role of needle biopsy in early diagnosis of lung lesions and incidence of lung lesions in needle biopsies in our hospital with respect to age and sex.A retrospective type of study. The histopathological records of our Hospital were reviewed for needle biopsies of lung lesions between January 2019 to December 2019 (One year). 35 cases noted during this period.There were a total of 35 cases during the study period of one year. The specimens received were linear bits and average size was 0.5cm in length. Non-neoplastic lesions were eight (22.85 %) and neoplasms contributed to 15 cases (42.85%) along with inadequate biopsies (20 %) and normal lung biopsies (14.28 %).Maximum number of cases were reported in the age group of 51-70 years (28 cases) with male preponderance. In all age groups, malignant lesions were more common in which, Adenocarcinoma was predominant. To conclude, in our study malignant neoplasms predominated over non neoplastic lesions. The most common histological type encountered in this study was an Adenocarcinoma.