METHOD: Institutions that publish pediatric dosing guidelines as a separate publication or as part of a hospital formulary were mailed a survey of questions to describe their publications. Publications that met the inclusion criteria were evaluated using twelve assessment criteria: approval or submissions by medical specialty groups, drug inclusion, dosing guidelines, dosing in organ failure, pharmacokinetic/pharmacodynamic parameters, therapeutic guidelines, intravenous (IV) and oral (PO) administration guidelines, adverse drug reactions/drug interactions, referencing, drug acquisition costs, organization, and readability. RESULTS: Nine hospital centres responded to the request for published pediatric dosing guidelines either as a separate publication or as part of a hospital formulary. Three centres were excluded that identified themselves as only publishing neonatal guidelines (Royal Victoria Hospital Montreal, Children's Hospital of Eastern Ontario Ottawa, Mount Sinai Hospital Toronto). One centre was excluded that only published an emergency manual for pediatrics (Ottawa Hospital Civic Site), and another centre only identified itself as publishing pediatric critical care dosing guidelines (London Health Sciences Centre). In addition, three Canadian pediatric publications were identified that incorporate pediatric dosing chapters in general reference handbooks: The similarities in these publications in combination with the consistency of drug information provided suggest that a collaboration of effort to produce a national pediatric publication may be justified. When reviewing these publications, it becomes evident that, for many drugs, there is a lack of evidence-based guidelines generated from well-designed pediatric clinical trials. Faced with this reality of few well-designed pediatric drug studies, these references have collated the available published information with institutional experience and historical practice to produce one of the few sources of pediatric dosing information. EFFECT OF DELIVERY TYPE ON BREASTFEEDING IN THE EARLY NEONATAL PERIODL Di Liddo, AM Carceller, M Gonthier, AC Bernard-Bonnin, I Fortier, I Chevalier OBJECTIVE: Breastfeeding is the optimal source of nutrition for term infants. Many factors influence its initiation and weaning. The goal of this pilot study was to determine breastfeeding initiation rates at SteJustine Hospital, a tertiary maternal and pediatric health care center. We also hypothesized that during hospitalization, the risk of formula supplementation and weaning in breastfed infants would be higher in infants delivered through cesarean section rather than vaginally. METHODS: We reviewed medical records of 234 healthy singleton infants greater than 35 weeks of gestational age born the first week of each month between March and June 2000. Abstracted data included: maternal prenatal intention regarding infant feeding, gestational age, sex, birth weight, analgesia during labour, delivery type, and infant feeding practice during hospitalization. Breastfeeding was ini...
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