We report substantially improved reaction conditions for palladium(II)-catalyzed tandem cyclization-intramolecular oxycarbonylation of (amino)polyols with a terminal double bond, based on utilization of iron pentacarbonyl [Fe(CO) 5 ] as an affordable and safe liquid supply of the carbonyl unit fully replacing gaseous carbon monoxide. Direct comparison with the classical version on a series of previously published substrates illustrates invariably shorter reaction times but comparable yields and selectivity.

Homogeneous Cyclocarbonylation of Alkenols with Iron Pentacarbonyl. -The Pd-catalyzed tandem cyclization-oxycarbonylation of (amino)polyols with a terminal double bond runs in a chemo-and stereoselective manner. -(BABJAK*, M.; MARKOVIC, M.; KANDRIKOVA, B.; GRACZA, T.; Synthesis 46 (2014) 6, 809-816, http://dx.doi.org/10.1055/s-0033-1340619 ; Dep. Org. Chem., Slovak Univ. Technol., SK-812 37 Bratislava, Slovakia; Eng.) -M. Tismer 35-035