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Musculo-skeletal complaints in a patient suffering from systemic lupus, with co-existing chronic renal failure, undergoing immunosuppressive treatment after kidney transplantation, can have a varied etiology. The aim of this work was to present a case based review of differential diagnosis of knee pain in such a patient. A literature search was carried out using MEDLINE/PubMed, Google Scholar and EBSCO, with no time limit. We undertook a systematic review of the literature published in English, limited to full-text publications of original articles, letters to the editor, and case reports in peer-reviewed journals, for a discussion and analysis of studies reporting arthralgia in patients with lupus after kidney transplantation. We present a case report of a 45-year-old woman with lupus nephritis, after kidney transplantation, who started to complain of increasing pain in the knees, most pronounced at night and after physical activity approximately 2 years after transplantation. Extensive causal diagnostics were carried out, which revealed bilateral extensive regions of bone infarction in the femur and tibia, chondropathy, degenerative changes of medial meniscuses in the body and posterior horn as well as chondromalacia of the patella. Establishing the right diagnosis is crucial for implementing appropriate treatment.

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An official journal of the Polish Society of Internal Medicine founded by professor Władysław Antoni Gluziński 7 Cancer epidemiology in chronic kidney disease. G. Piecha 9 Treatment of cancer in patients with chronic kidney disease: the nephrologist's point of view. M. Klinger 11 Chemotherapy in patients with chronic kidney disease: the oncologist's point of view. K. Sosińska-Mielcarek 13 Targeted therapies and chronic kidney disease. J. Małyszko 16 Radiation therapy in patients with chronic kidney disease. J. Chudek 18 Glomerulonephritis and tumors: the nephrologist's point of view. A. Oko 20 Renal manifestations of lymphoproliferative disorders. D. Wołowiec 22 Monoclonal gammopathy of renal significance: a nephrologist's perspective. K. Krzanowska 25 Thrombotic microangiopathy as a manifestation of cancer or a complication of chemotherapy. M. Myślak, J. Mazurkiewicz, M. Piątak 27 Kidney lesions secondary to malignancy: a pathologist's perspective. A. Perkowska-Ptasińska 29 Tumor lysis syndrome. M. Nowicki 31 Malignancy-related electrolyte and acid-base disorders. M. Domański, K. Ciechanowski 33 Dialysis in a patient with acute renal failure and malignancy. R. Gellert 35 Acute kidney injury in patients with cancer: the role of palliative care. M. Lichodziejewska-Niemierko 37 Progressive kidney failure in a patient with a neuroendocrine neoplasm treated with a somatostatin analogue. A. Zawiasa-Bryszewska, G. Mełeń-Mucha, M. Goździk, M. Wągrowska-Danilewicz, I. Kurnatowska 39 Membranous nephropathy: anti-PLA 2 R-guided diagnosis versus clinical reality. J. Borawski, B. Labij-Reduta, B. Naumnik 41 Cancer in patients with end-stage renal disease and kidney transplant recipients. L. Pączek, B. Czarkowska-Pączek, A. Ślizień-Dębska 43 The risk of cancer associated with immunosuppression in kidney transplant recipients. M. Sawosz, T. Bączkowska 45 Treatment of skin tumors in organ transplant recipients. B. Imko-Walczuk, D. Kadylak, A. Dębska-Ślizień 48 Cancer in a transplanted kidney. A. Dębska-Ślizień 50 New perspectives in the treatment of renal cell carcinoma. M. Matuszewski 52 Colorectal cancer secondary to kidney transplantation: a need for prophylaxis.