Background: Headache disorders are the third most frequent complaint in ambulatory care facilities, leading to an important loss of healthy years of life. Thus, it is important to study the factors related to hospitalizations due to these syndromes in Brazil. Objective: To describe the profile of hospitalizations due to migraine and other cephalic pain syndromes. Design and methods: This is an ecological study, based on secondary data with a descriptive approach. Data were collected from DATASUS regarding the number of hospitalizations, days spent in hospital, average cost per hospital stay, total amount of expenses, besides sex and age of hospitalized pacients due to migraine and other cephalic pain syndromes from 2011-2020. Results:78.058 hospitalizations were registered, with Southeast region’s prevalence (35.7%). The female and the economically active population (15-64 years) stand out in these results (65.8% and 79.9% respectively). The average permanence was of 3.84 days in SUS and the average value per hospital stay was R$ 407.77. The total amount spent on hospital services was R$ 28,153,255.86. Conclusion: The present study indicates a female and economically active population prevalence in hospitalizations. And also point out a Southeast region’s predominance in total amount of hospitalizations and second place regarding the costs on hospital services.