Microendoscopes based on optical fibres have recently come to the fore as promising candidates allowing in-vivo observations of otherwise inaccessible biological structures in animal models. Despite being still in its infancy, imaging can now be performed at the tip of a single multimode fibre, by relying on powerful holographic methods for light control. Fibre based endoscopy is commonly performed en face, resulting in possible damage of the specimen owing to the direct contact between the distal end of the probe and target. On this ground, we designed an all-fibre probe with an engineered termination that reduces compression and damage to the tissue under investigation upon probe insertion. The geometry of the termination brings the field of view to a plane parallel to the fibre’s longitudinal direction, conveying the probe with off-axis imaging capabilities. We show that its focusing ability also benefits from a higher numerical aperture, resulting in imaging with increased spatial resolution. The effect of probe insertion was investigated inside a tissue phantom comprising fluorescent particles suspended in agarose gel, and a comparison was established between the novel side-view probe and the standard en face fibre probe. This new concept paves the way to significantly less invasive deep-tissue imaging.

a b s t r a c tA fiber Bragg grating was inscribed in an abrupt fiber taper using a femtosecond laser and phase-mask interferometer. The abrupt taper transition allows to excite a broad range of guided modes with different effective refractive indices that are reflected at different wavelengths according to Bragg's law. The multimode-Bragg reflection expands over 30 nm in the telecom-C-band. This corresponds to a modefield overlap of up to 30% outside of the fiber, making the device suitable for evanescent field sensing. Refractive index and temperature measurements are performed for different reflection peaks. Temperature independent refractive index measurements are achieved by considering the difference between the wavelength shifts of two measured reflection peaks. A minimum refractive index sensitivity of 16 ± 1 nm/RIU was obtained in a low refractive index regime (1.3475-1.3720) with low influence of temperature (À0.32 ± 0.06 pm/°C). The cross sensitivity for this structure is 2.0 Â 10 À5 RIU/°C. The potential for simultaneous measurement of refractive index and temperature is also studied.

A brief review of new fiber microsphere geometries is presented. Simple microspheres working as Fabry-Perot cavities are interrogated in reflection and in transmission. Two microspheres were also spliced together, and subjected to different physical parameters. These structures are an alternative solution for load measurement and, when read in transmission, it is also possible to apply strain. Moreover, the structure is capable of being used under extreme ambient temperatures up to 900 • C. Random signal in cleaved microspheres was demonstrated with the possibility of using it for random laser or sensing applications. All this work was developed at the Centre for Applied Photonics, INESC TEC.