AimTo determine relation between near work and myopia progression in student population. Causes of myopia occurrence are not sufficiently explained.MethodsThis retrospective-prospective, descriptive research included 100 students with verified myopia up to -3 Dsph. Ophthalmological examination and measurement diopter-hours variable (Dh) were done twice, in the period from January 2011 until January 2012.ResultsA multivariate regression analysis of impact on the difference of distance visual acuity without correction to the right and left eye and difference of automatic computer refractometry in cycloplegia of both eyes indicates that, diopter-hours variable (Dh) had statistically significant impact on increase of distance visual acuity difference (right eye OR: I measurement–Dh 1.489, II measurement–Dh 1.544, p<0.05; left eye OR: I measurement–Dh 1.602, II measurement–Dh 1.538, p<0.05) and automatic computer refractometry in cycloplegia (right eye OR: I measurement 1.361, II measurement 1.493, p<0.05; left eye OR: I measurement 0.931, II measurement 1.019, p<0.05) during both measurements.ConclusionNear work cause the increase of myopia. This research opened a perspective for other researches on the impact of near work on myopia.

&lt;p&gt;&lt;strong&gt;Aim &lt;br /&gt;&lt;/strong&gt;To investigate biosynthesis in nitric oxide (NO) during normal pregnancy and in pregnancies complicated by preeclampsia. &lt;strong&gt;Methods&lt;br /&gt;&lt;/strong&gt; This prospective cross-sectional study included 80 patients hospitalized at the Department of Women&#039;s Health, Neonatology and Perinatology Cantonal Hospital in Zenica. Serum NO concentration in 20 non-pregnant women, 40 healthy pregnant women and 20 pregnant women with preeclampsia aged 17-40 years were measured. The group of healthy pregnant women were divided into 4 subgroups by gestational age. For each woman with preeclampsia, a healthy pregnant control was matched for age, parity and gestational age. Serum NO concentrations were determined after reduction of nitrates to nitrites using the Griess reaction. &lt;br /&gt;&lt;strong&gt;Results&lt;br /&gt;&lt;/strong&gt; NO concentrations during second trimester of pregnancy (37.2&amp;plusmn;1.7&amp;micro;M; p&amp;lt;0.05) and third trimester of pregnancy (40.9&amp;plusmn;2.8&amp;mu;M; p&amp;lt;0.05) were significantly higher in healthy pregnant women than in non-pregnant women (29.3&amp;plusmn;1.7&amp;mu;M). Serum NO concentrations were lower in preeclamptic women (30.7&amp;plusmn;1.8&amp;mu;M) compared to matched healthy pregnant women of the third and the late third trimester (35.1&amp;plusmn;2.2&amp;mu;M), without significant differences. Mean NO concentrations in pre-eclamptic women was positively correlated with systolic blood pressure (r=0.58; p&amp;lt;0.01), diastolic blood pressure (r=0.45; p&amp;lt;0.05), creatinine clearance (r=0.48; p&amp;lt;0.05), uric acid (r=0.49; p&amp;lt;0.05), and negatively correlated with platelet count (r=-0.57; p&amp;lt;0.05). &lt;br /&gt;&lt;strong&gt;Conclusion&lt;br /&gt;&lt;/strong&gt; NO production was increased with gestational age during normal pregnancy and slightly decreased in preeclampsia suggesting that NO may modulate the cardiovascular changes during normal pregnancy and pregnancy complicated by preeclampsia.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Aim&lt;/strong&gt; &lt;br /&gt;To investigate clinical presentation of COVID-19 infection in pregnancy, its course during pregnancy, effects on pregnancy&lt;br /&gt;outcomes for both mothers and newborns as well as the potential for vertical transmission.&lt;br /&gt;&lt;strong&gt;Methods&lt;/strong&gt; &lt;br /&gt;This retrospective observational study included all identifi ed COVID-19-positive pregnant women admitted to the Cantonal Hospital in Zenica at any stage of pregnancy or labour from 30 April 2020 to April 30 2021. Maternity and newborns were&lt;br /&gt;followed until discharge from the hospital.&lt;br /&gt;&lt;strong&gt;Results&lt;/strong&gt; &lt;br /&gt;Twenty-four pregnant women were positive for COVID-19. There were 79.2% asymptomatic cases, 12.5% had mild&lt;br /&gt;symptoms, while 8.3% had more severe forms of the disease. The main follow-up morbidities were high BMI 33.3%, anaemia 16.7%, thrombocytopenia 12.5%, hypertensive disorders 4.2% and diabetes 4.2%. The rate of premature births was 33.3%, while 8.3% pregnant women had premature rupture of the amniotic sac. Caesarean section was done for 75% women while 25% delivered vaginally. Previous caesarean section (54.2%) was the most common indication for operative completion of labour. Twentythree (92%) live babies were born, of which 8 (33.3%) were admitted to the neonatal intensive care unit. Two (8%) intrauterine foetal deaths were recorded that occurred before admission to our hospital. Two infants (8.7%) had a positive PCR test for COVID-19.&lt;br /&gt;&lt;strong&gt;Conclusion&lt;/strong&gt; &lt;br /&gt;COVID-19 viral disease in pregnancy is usually presented as an asymptomatic or mild disease. It is associated with&lt;br /&gt;high rates of preterm birth, admission of newborns to the intensive care unit and intrauterine foetal death. Vertical transmission is possible but the newborns were asymptomatic.&lt;/p&gt;