Studies of the spin and parity quantum numbers of the Higgs boson are presented, based on proton–proton collision data collected by the ATLAS experiment at the LHC. The Standard Model spin–parity JP=0+JP=0+ hypothesis is compared with alternative hypotheses using the Higgs boson decays H→γγH→γγ, H→ZZ⁎→4ℓH→ZZ⁎→4ℓ and H→WW⁎→ℓνℓνH→WW⁎→ℓνℓν, as well as the combination of these channels. The analysed dataset corresponds to an integrated luminosity of 20.7 fb−1 collected at a centre-of-mass energy of √s=8TeV. For the H→ZZ⁎→4ℓH→ZZ⁎→4ℓ decay mode the dataset corresponding to an integrated luminosity of 4.6 fb−1 collected at √s=7TeV is included. The data are compatible with the Standard Model JP=0+JP=0+ quantum numbers for the Higgs boson, whereas all alternative hypotheses studied in this Letter, namely some specific JP=0−,1+,1−,2+JP=0−,1+,1−,2+ models, are excluded at confidence levels above 97.8%. This exclusion holds independently of the assumptions on the coupling strengths to the Standard Model particles and in the case of the JP=2+JP=2+ model, of the relative fractions of gluon-fusion and quark–antiquark production of the spin-2 particle. The data thus provide evidence for the spin-0 nature of the Higgs boson, with positive parity being strongly preferre

We measure the time dependence of the ratio of decay rates for the rare decay D{0}-->K{+}pi{-} to the Cabibbo-favored decay D{0}-->K{-}pi;{+}. A signal of 12.7x10;{3} D{0}-->K{+}pi{-} decays was obtained using the Collider Detector at Fermilab II detector at the Fermilab Tevatron with an integrated luminosity of 1.5 fb;{-1}. We measure the D0-D[over ]{0} mixing parameters (R_{D},y{'},x{'2}), and find that the data are inconsistent with the no-mixing hypothesis with a probability equivalent to 3.8 Gaussian standard deviations.

We introduce a novel three-dimensional (3D) traction force microscopy (TFM) method motivated by the recent discovery that cells adhering on plane surfaces exert both in-plane and out-of-plane traction stresses. We measure the 3D deformation of the substratum on a thin layer near its surface, and input this information into an exact analytical solution of the elastic equilibrium equation. These operations are performed in the Fourier domain with high computational efficiency, allowing to obtain the 3D traction stresses from raw microscopy images virtually in real time. We also characterize the error of previous two-dimensional (2D) TFM methods that neglect the out-of-plane component of the traction stresses. This analysis reveals that, under certain combinations of experimental parameters (cell size, substratums' thickness and Poisson's ratio), the accuracy of 2D TFM methods is minimally affected by neglecting the out-of-plane component of the traction stresses. Finally, we consider the cell's mechanosensing of substratum thickness by 3D traction stresses, finding that, when cells adhere on thin substrata, their out-of-plane traction stresses can reach four times deeper into the substratum than their in-plane traction stresses. It is also found that the substratum stiffness sensed by applying out-of-plane traction stresses may be up to 10 times larger than the stiffness sensed by applying in-plane traction stresses.

During chemotactic movement, D. discoideum exhibits step-wise amoeboid motility driven by both contractile axial forces and lateral forces.