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The study area is located 100 km southeast of Arak and in two structural zones of Central Iran in the north and Sanandaj-Sirjan in the southern part. Regarding its geological structures, the area has become the source of important mines including the Akhtarchi gold mine, Aliabad iron mine, Ochestan feldspar mine, and Dali gold and copper mines. Therefore, promising areas for exploration activities are identified using the analysis of satellite images of ASTER and Landsat ETM + in the region to identify alteration areas. For this purpose, the necessary corrections were applied to the satellite images. Then, to identify the alteration parts related to the gold deposits, different satellite image processing methods of ETM + and ASTER were used.  These methods include making a false-color composite, band ratio, Selective Principal Components Analysis (SPCA), Spectral Angle Mapper (SAM) method, Spectral Information Divergence Classification (SID), Endmember Collection Dialog Components (ECDC), and innovative methods such as Principal Component Analysis (PCA) and Spectral Angle Mapper, as well as unsupervised classification methods. In the end, the major alterations in the region were observed. In the obtained images, the prophylitic zone and the phyllic and argillic zones in the region were observed. To introduce the optimal method, the results of the various methods mentioned were compared with each other and with the current situation of the mines. The alteration zones were identified through band ratio and SAM methods and the combined methods with more power. Finally, SAM, 2:1 ratio, and the combined methods were identified as successful methods for more accurate separation of the alteration zones.