AIM:Compare the basic characteristics of patients and to examine the existence of higher rates of perioperative complications (0 - 30 days) in women versus men after carotid endarterectomy (CEA).METHODS:This is a retrospective-prospective study included 270 patients with significant stenosis of carotid in whom CEA was performed, during the period from 2012 to 2017. Patients they were divided: group 1 - 100 female patients, group 2 - 170 male patients.RESULTS:No statistically significant age difference was observed between the two groups, group 1 - 66.01 years (SD 8.42, 46 to 86 years), group 2 - 66.46 years (SD 8.03, 47 to 85 years) (p = 0.659). Risk factors represent a greater prevalence in group 2, but the observed difference is not statistically significant. The average duration of surgery and the time of carotid artery clamping time were longer in group 1: (p = 0.002; p = 0.005). The number of classic endarterectomy with the patch was higher in women (41 (41%) versus 31 (18. 2%), p = 0.005), while the number of bilateral CEAs was not statistically significant.CONCLUSION:The results of this study of this study did not indicate a greater presence of perioperative complications (< 30 days) in women versus male patients after CEA.
The aim of the study was to investigate if preoperative blood flow velocity in femoral vein in different positions of the hip during total hip arthroplasty (thA) is a predictor of postoperative deep vein thrombosis (dvt). in patients undergoing thA, blood flow velocity and diameter of proximal femoral vein on thA side were measured preoperatively in four flexion positions of the hip. After thA, patients were followed up for 42 days for dvt occurrence, and clinical features of patients with and without postoperative dvt were compared. The mean blood flow velocity in maximal flexion (90º+) preoperatively was significantly lower in patients with postoperative dvt (19/103) compared to patients without it (8.4±2 cm/s vs. 10.6±2.3 cm/s; p<0.001). using the receiver operating characteristic curve analysis, the cutoff value for blood flow velocity during maximal flexion was 8.24 cm/s. in addition, anesthesia duration, duration of surgical position of the patient, body mass index, amount of blood transfused after surgery, and clinical signs of dvt were markedly different between patients with and those without postoperative dvt. blood flow velocity in femoral vein in maximal flexion of the hip (90º+) measured prior to thA is an independent predictor of postoperative dvt.
<p><strong>Aim <br /></strong>To evaluate the incidence, modalities of treatment and outcome in paediatric patients with traumatic brain injury (TBI). <strong>Methods <br /></strong>A retrospective cross-sectional study including 353 paediatric patients with head injury was carried out in the Department of Neurosurgery of University Clinical Centre Sarajevo during the period 1 July 2006-30 June 2012 (72 months). For each patient the lowest Glasgow Coma Scale (GCS) was established and the patient was accordingly classified as suffering from mild, moderate or severe TBI. Neuroimaging data included computer tomography (CT). Survival rates and method of treatment were compared according to age group, and matched with the total number of patients examined. <br /><strong>Results<br /></strong> A total of 353 children with head trauma were identified. A severe TBI (GCS &lt; 8) was found in 33 (out of 353) children, mostly in the age group 11-18. Falls were the most common cause of trauma, followed by traffic accidents. Falls were the most common mechanism in the infants, preschool, and school children up to 10 years old; children aged 11-18 showed a higher rate of traffic accidents comparing to children younger than 3 years. Of 353 patients, 49 (13,9%) required surgical procedure, 304 (86.1%) were threated conservatively. Survival rate was 96.6 %. <br /><strong>Conclusion<br /></strong> The majority of hospitalized patients qualify for medical treatment and surgical intervention is reserved for selected cases. Thus, the adequate pre-hospital care is essential.</p>
<p><strong>Aim</strong> <br />To investigate the serum value of brain derived neurotrophic factor (BDNF), proteins S-100, NSE, IL-6 in normal pressure patients (NPH) compared to control (healthy) group and also a possible correlation with radiological findings in NPH patients.<br /><strong>Methods</strong> <br />Study patients were included during the period of 2020-2022. All NPH patients met the diagnostic criteria for probability<br />of NPH. Control patients group included patients without known brain disorder, without clinical symptoms of NPH. Blood samples were taken before planned surgery for NPH. BDNF serum concentrations were assessed by a sensitive ELISA kit, and serum concentrations of S-100, NSE and IL-6 were assessed by using ECLIA technology for immunoassay detection.<br /><strong>Results</strong> <br />Among 15 patients who were included, seven NPH patients were compared to eight control patients. Non-significant<br />decrease in BDNF serum concentrations, an increase of protein S-100 serum concentrations, a decrease of NSE serum concentrations, as well as an increase of IL-6 serum concentrations in NPH patients compared to healthy controls was found. Strong positive correlation between BNDF and Evans index was observed (p=0.0295).<br /><strong>Conclusion</strong> <br />We did not find a significant difference of BDNF, protein S-100, IL-6 and NSE between serum concentration in NPH<br />and healthy patients. More future research is needed to find the<br />role of BDNF in NPH patients.</p>
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