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Pumpkin (Curcurbita maxima) is a popular vegetable in our country. This plant is locally known as "Mistikumra". The seeds of pumpkin are rich in oil and nutrients. The nutritional compositions of pumpkin seeds were determined by standard method. The proximate compositions of the powdered seed were moisture 4.06%, ash 3.80%, crude fibre 2.91%, total lipid 36.70%, total protein 34.56%, total soluble protein 18.10%, sugar 1.08%, and starch 2.15%. The minerals composition of the seed were nitrogen 5.53%, phosphorus 0.71%, sodium 4.80 Cmol/kg, potassium 20.00 Cmol/kg, Calcium 4.40 Cmol/kg, Magnesium 348.7 ppm, iron 290.0 ppm, coper 70 ppm, zinc 39.9 ppm, and manganese 17.9 ppm. It is used as a potentially attractive source of lipid, protein and crude fibre. The oil was extracted from seed of Cucurbita maxima by solvent extraction process using petroleum ether (40°-60°C). The oil content was found to be 12%. The specific gravity of the oil was estimated to be 0.9412 at 31°C. GLC analysis of oil indicated that it contained highest amount of oleic acid 40.58%, while stearic acid, palmatic acid and linoleic acid contents were found to be 27.06%, 17.39% and 14.97% respectively. In addition, the iodine value, saponification value, saponification equivalent, acid value and percentage of free fatty acid of seed oil were determined by standard method and found to be 114.33, 193.73, 289.58, 0.516 and 0.2646% respectively. High degree of unsaturation makes it suitable for using as valuable drying agent, and lower free fatty acid content indicates suitability of the oil for probably edible purpose. Cururbita maxima seed oil is a rich source of linoleic acid, which is useful in human body.

Introduction: Febrile convulsion is the most common seizure disorder in the pediatric age group. It occurs in 2-5% of children. A febrile seizure is a seizure accompanied by fever (temperature 100.4°F or 38°C by any method), without central nervous system infection, that occurs in infants and children 6 through 60 months of age. Aim: The study was conducted to see the effect of serum sodium level on the recurrence of febrile seizure during the same febrile illness. Materials and Method: A cross-sectional descriptive study which enrolled 65 children admitted with febrile seizures at 100 bed district hospital, Naogaon. They were divided in to two groups, those with a single seizure and the rest were children with more than one seizures. Serum sodium levels were estimated after stabilization of patients. The probability of recurrent febrile seizures and serum sodium level was analyzed. Results: Hyponatremia (serum sodium <135 mmol/l) was seen in 12(18.5%) of 65 children and the remaining 81.5% children had normal serum sodium level (serum sodium 135-145 mmol/l). Among the hyponatremia group all children developed more than one seizure during the same febrile episode. The mean serum sodium level in patients with single and recurrent seizure was 138.48±2.17mmol/l and 135.27±3.11mmol/(P<0.001). The relationship between the probability of a recurrent seizure and serum sodium level is statistically highly significant. Conclusion: Estimation of the seum sodium in children with febrile seizures help in deciding for admission in hospital as well as to predict seizure recurrence within the same febrile episode. TAJ 2019; 32(1): 39-45

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Congenital heart disease is most common heart disease in children and causes significant morbidity and mortality. This study was done to evaluate the frequency and pattern of congenital heart disease in neonates (age ≤ 28 days) admitted in a tertiary care level hospital. It was a cross-sectional descriptive type of study conducted at the Department of Paediatrics of Rajshahi Medical College Hospital from January 2014 to December 2015. Among the 4120 neonates admitted in RMCH in that period, 52 cases had cardiac murmur on auscultation. Incidence of cardiac murmur in the newborn was 1.26%. Clinically, among the 52 cases, 40 cases were thought to have pathological murmur and 12 cases were thought to have innocent murmur. During echocardiography, structural cardiac defect (congenital heart disease) was detected in 38 cases. So, incidence of congenital heart disease was 9.22/ 1000 live births. Remaining 14 cases had normal cardiac anatomy in echocardiography. VSD (12 cases) was the most common type of acyanotic congenital heart disease (23.08%) followed by ASD (11 cases) and PDA (6 cases). Among the cyanotic congenital heart disease, tetralogy of Fallot was the most common abnormality and it was found in 4 cases (7.69%). In this study, parental consanguinity was detected in 4 cases (7.69%). Early diagnosis, timely referral and proper management of congenital heart can save valuable lives and allow normal growth and development. TAJ 2018; 31(2): 35-38