This research note addresses a gap in the public administration literature by arguing that a political Darwinism was present in the intellectual origins of American administrative theory. By examining the arguments of Woodrow Wilson, this article demonstrates that Darwinism complemented the German political thought that contributed to the establishment of America’s administrative state. The application of Darwinian evolutionary biology to politics was a vital element of Wilson’s reconceptualization of the state as a living organism. Darwinism was a key rhetorical tool employed by Wilson in his argument against the Constitution’s separation of powers. This note finds that Darwinism was present in the early stages of public administration theory in Wilson’s argumentation and persists today in the public administration literature. It concludes by sketching out an agenda for further research on Darwinism’s influence on public administration.