The present experiment was carried out under the Shade net, Research Field, Department of Horticulture, SHUATS, Prayagraj during the month of November 2021 to February 2022. Experiment was laid out in Randomized Block Design (RBD), with eight treatments, replicated thrice with nutrient field technique hydroponics system and lettuce variety Grand Rapids. The treatments were T1 (NPK 2.8ml/Plant), T2 (NPK 4.2ml/Plant), T3 (NPK 5.71ml/Plant), T4 (NPK 7.14ml/Plant), T5 (NPK 8.57ml/Plant), T6 (NPK 10ml/Plant), T7 (NPK 11.43ml/Plant) and T8 (NPK12.86ml/Plant). From the observations T5 was found to be the best relating to growth and yield parameters followed by T6 and T7. In gross return, net return and B.C maximum values were also recorded in T5.