The presence of small intestinal diverticula was examined in a family of eight siblings. Six of the siblings had diverticula of the duodenum and/or the jejunoileal tract. Three of them had multiple jejunoileal diverticula, one had two jejunal diverticula, and two had duodenal diverticula. In addition, diseases of an immunologic nature were present in four of the siblings (rheumatoid arthritis, ulcerative colitis, myxoedema following thyroiditis, and non-viral hepatitis).

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ABSTRACT. In a prospective randomized clinical trial comprising 22 postmenopausal women with backache and a halisteretic spine with crush fracture(s), 12 women completed a 12‐week therapy with sodium fluoride, calcium and calciferol and 10 with placebo. A statistically significant improvement (p > 0.05), evaluated by a four‐stage scale on pains, infirmity, and consumption of analgesics, was observed in the actively treated patients.

Previous observations of changes of tubular reabsorptive capacity for glucose (TmG/GFR ratio) as a consequence of parathyroid disorder are supported by the results of a follow‐up study of an additional fortyfive patients. A distinct separation by TmG/GFR ratio exists in patients with hyper‐ and hypoparathyroidism. In five of thirty‐three patients with hyperparathyroidism (15%) the values of TmG/GFR ratio were within mean ± 2 S.D. of the values obtained in twenty‐four control patients. Parathyroid extract increases and removal of parathyroid adenoma or suppression of the parathyroid function by i.v. calcium decreases the ratio. The value of a clinical application of this physiologic phenomenon is discussed. The ratio might well point to the actual parathyroid function. An increased ratio, however, does not illustrate whether a hyperparathyroidism is autonomous, secondarily stimulated, or due to secretion of a parathyroid hormone‐like substance. And a decreased ratio does not exclude hyperparathyroidism since three patients with hyperparathyroidism due to water‐clear cell affection showed low values of the ratio. Finally, other factors than parathyroid hormone influence the reabsorptive capacity for glucose. In excluding coexisting hyperparathyroidism in hypercalcemic sarcoidosis, and, probably, in separation of idiopathic hypercalcuria into a renal form with stimulated parathyroid function and an intestinal form with suppressed parathyroid function, determination of the TmG/GFR ratio might be valuable.

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