Traditional rehabilitation discharge summaries lacked information relevant to rehabilitation care. Information capture and total relevant report content increased significantly after SDMM integration into reports.
With an aging population, chronic low back pain will continue to increase as a source of disability and pain for many patients. This degenerative process can be attributed to a number of diagnoses including spinal stenosis, facet arthropathy, degenerative disc disease (DDD), and herniated nucleus pulposus. These diagnoses have a number of nonregenerative treatment options, including medications, therapy, and traditional interventional procedures. As these treatments are not always successful, novel regenerative treatment options such as platelet-rich plasma (PRP), bone marrow-derived mesenchymal stem cells (MSCs), and growth factors need to be explored. These regenerative therapies are proposed to promote healing, repair, and regeneration of tissue. The use of PRP in spinal fusion has been studied, but there is conflicting evidence affecting spinal fusion rates, and the efficacy is uncertain. PRP and MSCs have been evaluated in the treatment of DDD. Studies show both may have a role in preventing DDD; however, the use of bone marrow-derived stem cells has shown more promising data. This article discusses the available research for regenerative options for the treatment of low back pain. Unfortunately, there is a paucity of literature which examines the use of regenerative medicine as treatment for the wide spectrum of pathologies which cause this common condition. More research is needed to further establish the effective use of PRP, bone marrow-derived stem cells, and growth factors for the treatment of low back pain. Keywords Regenerative medicine Á Stem cell Á Low back pain Á Platelet-rich plasma (PRP) Common Causes and Presentation of Low Back Pain Low back pain is a vague description of a number of different diagnoses that are primarily related to mechanical factors [1]. These include: muscular strain, spinal stenosis, facet-mediated pain, degenerative disc disease (DDD), and
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