Background: The study aimed to get drug utilization pattern using WHO prescribing indicators in pediatric patients. Methods: It was an observational prospective study carried out in pediatric in-patients with a sample size of 280 patients based on inclusion, and exclusion criteria for a period of 6 months. The study data were collected using patient case record and analysis was done. Results: Out of 280 patients data collected, majority of patients were in the gender male category 168 (60%) and many were from the age group of early childhood (1-5 years) 126 (45%). Respiratory tract infections were the major diagnosis made among the sample size. The drug class commonly prescribed were oral antibiotics 261 (28.38%). The average number of drugs per prescription were 3.28%. Among the total number of prescription percentage of drugs prescribed by generic name and antibiotics were 2.7%, 76.07%. Percentage of patients prescribed with injection were 79.28%. Conclusions: This study highlights WHO prescribing core indicators in evaluating the usage of rational prescription. It helps in reinforcing rational prescribing practices and increases awareness among physicians and medical students. Irrational prescriptions may result in harmful events. A rational prescription should follow the standard treatment guidelines of WHO. The assessment of these indicators can also help us to decrease the cost burden on the patient. Continuous education with focus on rational drug usage and evidence-based medicine can further increase the understanding and improves health care policies.

Due to variety of pediatric population and barriers of modern technologies it looks that a single formulation strategy will now not be suited for all pediatric patients. The determination of a suitable formulation strategy for a targeted population crew wants to be cautiously considered for every individual product. When managing patients who can't swallow solid oral dosage forms, switching to choice liquid components or different route is greater suitable. To limit unnecessary drugs manipulation it is fundamental for prescribers to think about age appropriateness, type of formulation (in relation to ease of administration), swallowing issues and patient capability to swallow. Palatability needs to be considered carefully by pharmaceutical companies when designing new formulations and also by prescribers in order to optimize effective prescribing, adherence, therapeutic results and lowering wastage with cost savings. . Majority of drugs prescribed for children have not been competently examined in pediatric population. Future formulation work needs to be carried out to strengthen pediatric based formulations. Formulations accepted by children need to be accessible in suitable unit doses covering child dosing ranges and it should be able to tapered accordingly. Monolithic solid dosage form was discovered to be an alternative choice in case of unavailable liquid dosage form. It is very necessary therefore that all requests to crush, split, or opening of capsules have to be discussed with clinical pharmacist prior to beginning administration of the crushed products.