This retrospective study evaluates outcomes after treatment of upper-extremity soft tissue sarcoma in 44 patients. We re-resected 19 tumours that had been resected elsewhere without adequate preoperative planning, and we made 25 well-planned primary resections. Four patients in the unplanned group and five in the planned group eventually received amputations. Thirty-three patients were alive at a median follow-up time of 33 months (IQR 18 to 57). Tumour size > 7 cm, tumour Grade 3 and the presence of distant organ metastases were the main factors affecting the oncological outcomes. We found no statistical differences between the planning groups. Functional outcomes and quality of life were significantly worse after amputation or major nerve resections. We conclude with this sized sample that the lack of planning in itself did not influence the final results, but there were differences in tumour size, grade and localization between the groups that may play a role. Level of evidence: IV

Objective: We aimed to investigate the characteristics of patients who underwent unilateral amputation due to diabetes and peripheral artery disease, as well as the risk factors that cause re-amputation, and to determine these patients' survival status and the risk factors for mortality. Patients and Methods: This retrospective study included 133 patients who underwent amputation due to diabetes and peripheral arterial disease between 2012 and 2018. The etiology of amputation, the re-operation rate and time to re-operation following initial amputation, survival status and follow up results were accessed from hospital records. Results: Twenty-eight patients underwent amputation due to peripheral arterial disease, whereas 105 patients had peripheral vasculopathy due to diabetes mellitus. The re-operation rate was 33.8%, and the median period from initial surgery to the second surgery was six-weeks. Sixty-six deceased patients survived with a median of 6 months following initial operation. Conclusion: The most crucial factor causing re-amputation was the non-healing wound problems. Patients with amputation should be followed up carefully for wound problems in the six weeks after surgery. Advanced age, American Society of Anesthesiologist grade 4 patients, associating neurological disease, low albumin level, low lymphocyte count and postoperative intensive care unit requirement were all poor prognostic factors for survival. Re-amputation had no negative effect on survival.