The aim of this study was to evaluate the effectiveness of the non-surgical periodontal treatment in reducing the gingival crevicular fluid (GCF) levels of IL-18 from inflamed periodontal sites. Fourteen patients with periodontal disease were included, being 9 patients with chronic periodontitis (mean age: 48.8 SD ± 7.4 years) and 5 patients with gingivitis (mean age: 43.6 SD ± 11.8). The patients were divided in the following groups: gingivitis sites from periodontitis patients (sites GP), periodontitis sites from periodontitis patients (sites PP), and gingivitis sites from gingivitis patients (sites GG). Probing pocket depth (PPD), probing attachment level (AL), plaque index (PI) and gingival index (GI) were recorded, and gingival fluid samples were collected. The subjects received non-surgical treatment and were re-evaluated 30 days after treatment (day 30 AT). There was a significant reduction in PI in GG (1.0 ± 0.4 to 0.5 ± 0.2), GP (1.2 ± 0.3 to 0.5 ± 0.3), and in PP (1.3 ± 0.4 to 0.7 ± 0.3) 30 AT. There was also a significant reduction in the GI in GG (1.3 ± 0.3 to 0.7 ± 0.4). PPD reduced significantly in GG (2.4 ± 0.6 to 1.9 ± 0.1), and PP (6.7 ± 1.1 to 5.2 ± 0.9) 30 AT. When all the samples were analyzed together, there was a significant reduction in IL-18 (12.9 ± 7.2 to 10.0 ± 3.1). This study showed that non-surgical treatment was effective in reducing GCF levels of IL-18 from inflamed periodontal sites.
O tratamento de recessões gengivais além de proporcionar maior conforto ao paciente diminuindo a sensibilidade restabelece o posicionamento normal do tecido gengival melhorando a estética. Procedimentos cirúrgicos rápidos e com menor sintomatologia dolorosa seriam ideais na prática clínica para o recobrimento radicular. Dessa forma, biomateriais substitutos a enxertos autógenos estão cada vez mais sendo pesquisados. Assim, o objetivo deste estudo é verificar sob revisão da literatura científica atualizada, artigos clínicos que realizaram o recobrimento radicular em recessões dentais unitárias utilizando do Mucograft® comparativamente aos enxertos autógenos. Para isso, o termo Mucograft® foi utilizado para buscas no Pubmed e Google e 48 resultados foram obtidos. Desses, 9 artigos foram selecionados. 6 estudos avaliaram a porcentagem de recobrimento radicular, enquanto que 2 avaliaram o aumento da faixa de tecido queratinizado e 1 as mudanças histológicas. O uso de Mucograft® demonstrou resultados positivos em relação a capacidade de recobrimento radicular com boa estética e nível de dor pós operatória semelhante ao do obtido pelo enxerto autógeno. As evidências científicas demonstram que o a Matriz Mucograft® é um material promissor, mas comprovações com maior tempo de acompanhamento são necessárias para auxiliar o clínico nas suas escolhas.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.