Deep brain stimulation (DBS) surgery is most effective in reducing the symptoms of Parkinson's disease and essential tremor. At present, there is no designated instrumental method for measuring the immediate effects of DBS. This paper presents the concept of a glove monitoring system for DBS. With the benefits of microelectromechanical systems, inertial measurement unit, and force sensitive resistor (FSR), the system is portable and can be integrated into a textile glove. Tremors, bradykinesia, and rigidity assessments are performed by the system. Several test tasks are chosen to be performed during DBS surgery to evaluate the electrode's position and stimulation intensity. Each quantified symptom severity of the patient is added to a list shown in the graphical user interface for comparison. Comparative experiments between the prototype and an electromagnetic motion tracking system were presented. The FSR boxes were validated with weights. Experimental results show that this system is reliable for tremor amplitude determination, movement angles measurement, and resistance measurement to a passive movement. In addition, it can be found that inconsistent tremor movements have an influence on the tremor amplitude calculation done with power spectral density estimation.Index Terms-MEMS IMU, glove monitoring system, parkinson's disease quantitative assessment, tremor, bradykinesia, rigidity, reliability testing.

Rigidity is one of the primary symptoms of Parkinson's disease. Passive flexion and extension of the elbow is used to assess rigidity in this study. An examiner flexes and extends the subject's elbow joint through a rigidity assessment cuff attached around the wrist. Each assessment lasts for 10 seconds. Two force sensor boxes and an inertial measurement unit are used to measure the applied force and the state of the elbow movement. Elastic and viscous values will be obtained through a least squares estimation with all the data. 9 healthy subjects were tested with this system in two experimental conditions: 1) normal state (relaxed); 2) imitated rigidity state. Also the subjects were performed the assessment task with different frequencies and elbow movement ranges. The imitated rigidity action increases viscosity and elasticity. The effect sizes (Cohen's d) of the viscosity and elasticity between normal state and imitated state are 1.61 and 1.36 respectively, which means the difference is significant. Thus, this system can detect the on-off fluctuations of parkinsonian rigidity. Both wrist movement angle and frequency have small effect on the viscosity, but have elevated effect on the elasticity.